Nuttall Elle, Wehrmann Daniel
Otolaryngology-Head and Neck Surgery, Creighton University, School of Medicine, Omaha, USA.
Otolaryngology-Head and Neck Surgery, Children's Hospital and Medical Center, Omaha, USA.
Cureus. 2022 Apr 14;14(4):e24136. doi: 10.7759/cureus.24136. eCollection 2022 Apr.
Necrotizing sialometaplasia is a rare, benign disease that affects any area containing minor salivary glands. This entity presents a diagnostic difficulty due to its resemblance to malignancy. A unique case of bilateral asynchronous necrotizing sialometaplasia with superinfection secondary to trauma is described in this study. A 19-year-old female presented with bilateral ulcerative lesions in her buccal mucosa and facial swelling. The two lesions appeared several weeks apart. The diagnostic workup excluded rheumatologic, malignant, and infectious etiologies. The patient was treated with antibiotics and steroids with subsequent resolution of symptoms. Given the exclusion of other etiologies, the patient was diagnosed with bilateral asynchronous necrotizing sialometaplasia with superinfection. This case demonstrates the importance of considering necrotizing sialometaplasia as a diagnosis in all patients with oral ulcerative lesions.
坏死性涎腺化生是一种罕见的良性疾病，可累及任何含有小涎腺的区域。由于其与恶性肿瘤相似，该疾病存在诊断困难。本研究描述了一例因创伤继发感染导致的双侧异步坏死性涎腺化生的独特病例。一名19岁女性患者出现双侧颊黏膜溃疡性病变及面部肿胀。两处病变相隔数周出现。诊断检查排除了风湿性、恶性和感染性病因。患者接受抗生素和类固醇治疗后症状缓解。由于排除了其他病因，该患者被诊断为双侧异步坏死性涎腺化生伴继发感染。该病例表明，对于所有患有口腔溃疡性病变的患者，考虑将坏死性涎腺化生作为一种诊断的重要性。
