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本文引用的文献

1
[Pediatric esthesioneuroblastoma: an exceptional malignant lesion (a case study and literature review)].[小儿嗅神经母细胞瘤：一种罕见的恶性病变（病例报告及文献综述）]
Pan Afr Med J. 2018 Oct 25;31:144. doi: 10.11604/pamj.2018.31.144.16807. eCollection 2018.
2
An Unusual Presentation of Esthesioneuroblastoma in a Young Pregnant Female.一名年轻怀孕女性的嗅神经母细胞瘤罕见病例报告
Ocul Oncol Pathol. 2018 Apr;4(3):192-195. doi: 10.1159/000481507. Epub 2017 Nov 18.
3
Olfactory Neuroblastoma: A Rare Cause of External Ophthalmoplegia, Proptosis and Compressive Optic Neuropathy.嗅神经母细胞瘤：导致眼球外肌麻痹、眼球突出和压迫性视神经病变的罕见病因。
Turk J Ophthalmol. 2018 Apr;48(2):92-94. doi: 10.4274/tjo.81568. Epub 2018 Apr 25.
4
Olfactory neuroblastoma presenting with exclusive orbital manifestations.
J Craniofac Surg. 2013 Mar;24(2):667-9. doi: 10.1097/SCS.0b013e3182802053.
5
Esthesioneuroblastoma presenting with proptosis and bilateral neck metastasis: An unusual presentation.以眼球突出和双侧颈部转移为表现的嗅神经母细胞瘤：一种不寻常的表现。
J Pediatr Neurosci. 2011 Jan;6(1):78-81. doi: 10.4103/1817-1745.84417.
6
Olfactory neuroblastoma.嗅神经母细胞瘤。
Head Neck Pathol. 2009 Sep;3(3):252-9. doi: 10.1007/s12105-009-0125-2. Epub 2009 Jul 16.
7
Esthesioneuroblastoma: a meta-analysis and review.嗅神经母细胞瘤：一项荟萃分析与综述
Lancet Oncol. 2001 Nov;2(11):683-90. doi: 10.1016/S1470-2045(01)00558-7.
8
Third nerve palsy as the presenting manifestation of esthesioneuroblastoma.第三神经麻痹作为嗅神经母细胞瘤的首发表现。
J Neuroophthalmol. 2000 Mar;20(1):20-1. doi: 10.1097/00041327-200020010-00007.
9
Esthesioneuroblastoma: prognosis and management.嗅神经母细胞瘤：预后与治疗
Neurosurgery. 1993 May;32(5):706-14; discussion 714-5. doi: 10.1227/00006123-199305000-00002.
10
Ophthalmic manifestations of esthesioneuroblastoma.嗅神经母细胞瘤的眼部表现。
Ophthalmology. 1985 Dec;92(12):1749-53. doi: 10.1016/s0161-6420(85)34102-7.

嗅神经母细胞瘤：一种不寻常的眼部表现。

Olfactory Neuroblastoma: An Unusual Ocular Presentation.

作者信息

AlQahtani Dhabiah Saeed, Alshamrani Abdulaziz A, AlQawahmed Raniah, Elkhamary Sahar, AlGhadeer Huda

机构信息

Ophthalmology Department, King Khaled Eye Specialist Hospital, Riyadh, Kingdom of Saudi Arabia.

Pathology Department, Prince Sultan Military Medical City, Riyadh, Kingdom of Saudi Arabia.

出版信息

Neuroophthalmology. 2021 Aug 25;46(3):182-185. doi: 10.1080/01658107.2021.1958872. eCollection 2022.

DOI:10.1080/01658107.2021.1958872
PMID:35574165
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9103352/
Abstract

We report a case of 51-year-old medically healthy male who presented with gradual painless diminution of vision in both eyes for 3 months. His visual acuity was hand movement perception in the right eye, and no light perception in the left eye. The intraocular pressure, external eye examination, ocular motility and anterior segment examinations were normal. Fundus examination revealed severe bilateral papilloedema and engorged tortuous veins in both eyes. Imaging exhibited a large intracranial tumour causing raised intracranial pressure. This was debulked by neurosurgery and histological examination revealed that the tumour was an olfactory neuroblastoma (ONB). This case is noteworthy since ONBs rarely present with isolated papilloedema without any accompanying ophthalmoplegia, proptosis, epistaxis, nasal, or neurological symptoms.

摘要

我们报告一例51岁身体健康的男性，其双眼视力逐渐无痛性下降3个月。右眼视力为手动，左眼无光感。眼压、外眼检查、眼球运动及眼前节检查均正常。眼底检查发现双眼严重视乳头水肿及迂曲扩张的静脉。影像学检查显示一个巨大的颅内肿瘤导致颅内压升高。经神经外科手术切除肿瘤，组织学检查显示该肿瘤为嗅神经母细胞瘤（ONB）。该病例值得注意，因为嗅神经母细胞瘤很少仅表现为孤立的视乳头水肿，而无任何伴随的眼肌麻痹、眼球突出、鼻出血、鼻部或神经症状。