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颅内血栓的高分辨率扫描电子显微镜分析,这些血栓沿着支架取栓器嵌入。

A high resolution scanning electron microscopy analysis of intracranial thrombi embedded along the stent retrievers.

机构信息

Neuroradiagnostic and Neurointerventional Division, Department of Radiology and Medical Informatics, Faculty of Medicine, University of Geneva, Geneva, Switzerland.

Division of Diagnostic and Interventional Neuroradiology, HUG Geneva University Hospitals, Geneva, Switzerland.

出版信息

Sci Rep. 2022 May 16;12(1):8027. doi: 10.1038/s41598-022-11830-4.

Abstract

Endovascular treatment with stent retriever thrombectomy is a major advancement in the standard of care in acute ischemic stroke (AIS). The modalities through which thrombi embed along stent retriever following mechanical thrombectomy (MTB) have not yet been elucidated. Using scanning electron microscopy (SEM), we analyzed the appearance of thrombi retrieved by MTB from AIS patients, when embedded into the stent retriever. We observed that the organization and structural compactness vary for compositionally different thrombi. The modalities of attachment onto the stent vary according to thrombus composition and organization.

摘要

血管内治疗采用支架取栓术是急性缺血性脑卒中(AIS)治疗标准的重大进步。机械血栓切除术(MTB)后支架取栓术中血栓嵌入支架的方式尚不清楚。我们使用扫描电子显微镜(SEM)分析了从 AIS 患者的 MTB 中取出的血栓嵌入支架取栓器后的外观。我们观察到,组成不同的血栓其组织结构和结构紧凑度有所不同。血栓的附着方式根据血栓的组成和组织而有所不同。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d8ef/9110407/856a5597a42d/41598_2022_11830_Fig2_HTML.jpg

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