Goodsitt M M, Rosenthal D I, Reinus W R, Coumas J
Invest Radiol. 1987 Mar;22(3):209-15. doi: 10.1097/00004424-198703000-00005.
Two dual-energy CT techniques have been developed to analyze the mineral and fat content of trabecular bone. Both are postprocessing techniques that employ calibration standards. Experiments were performed to test these techniques against conventional single-energy techniques and two other dual-energy techniques. As expected, all of the dual-energy methods estimate the mineral content more accurately when fat is present. In contrast to the other dual-energy methods, the new methods described in this article are unique because they make a separate estimate of the fat content of the bone. The results of preliminary tests of these techniques in estimating fat content have been encouraging. Although not exact, the estimates show the correct trend in increasing proportionately as the fat content increases. Possible applications of the techniques in the study of osteoporosis and other bone diseases are described.
已经开发出两种双能CT技术来分析小梁骨的矿物质和脂肪含量。这两种都是采用校准标准的后处理技术。进行了实验，将这些技术与传统单能技术及其他两种双能技术进行对比测试。正如预期的那样，当存在脂肪时，所有双能方法对矿物质含量的估计都更准确。与其他双能方法不同，本文所述的新方法很独特，因为它们能单独估计骨骼的脂肪含量。这些技术在估计脂肪含量方面的初步测试结果令人鼓舞。尽管并不精确，但这些估计显示出随着脂肪含量增加而成比例增加的正确趋势。文中还描述了这些技术在骨质疏松症和其他骨病研究中的可能应用。
