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原发性恶性肺黑色素瘤一例报告

A Case Report of Primary Malignant Pulmonary Melanoma.

作者信息

Balcı Akın Eraslan, Kılıç Murat, Çalık İlknur, Murat Ayşe

机构信息

Department of Thoracic Surgery, Euphrates University Hospital, Elazığ, Turkey.

Department of Pathology, Euphrates University Hospital, Elazığ, Turkey.

出版信息

Turk Thorac J. 2022 May;23(3):257-260. doi: 10.5152/TurkThoracJ.2022.19062.

DOI:10.5152/TurkThoracJ.2022.19062
PMID:35579233
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9450113/
Abstract

We operated on primary malignant melanoma of the lung, attaching the pericardium, diaphragm, and parietal pleura. A 48-year-old female was admitted to our hospital because of persistent dyspnea and cough. A preoperative computed tomography of the chest revealed 3 lesions in the right lung and a mass on the diaphragm between the right lung's lower lobe and heart. A middle lobectomy was performed. The mass on the diaphragm had invaded the diaphragm and pericardium strictly. With a pericardiectomy and a diaphragmatic resection, the mass was removed in an en-bloc manner. Adjuvant chemotherapy was started 1 month after surgery and consisted of 5 days course of iv injection of cisplatin (90 mg/kg). The follow-up period was 5 years and uneventful. For primary pulmonary melanoma, even if it has intrapulmonary metastases, surgery and adjuvant chemotherapy can provide uneventful survival for more than 5 years.

摘要

我们对原发性肺恶性黑色素瘤进行了手术,切除范围包括心包、膈肌和壁层胸膜。一名48岁女性因持续呼吸困难和咳嗽入院。术前胸部计算机断层扫描显示右肺有3个病灶,右肺下叶与心脏之间的膈肌上有一个肿块。行右肺中叶切除术。膈肌上的肿块已严格侵犯膈肌和心包。通过心包切除术和膈肌切除术,将肿块整块切除。术后1个月开始辅助化疗,采用静脉注射顺铂(90mg/kg),疗程为5天。随访期为5年,过程顺利。对于原发性肺黑色素瘤,即使有肺内转移,手术和辅助化疗也可使患者顺利存活5年以上。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f7ab/9450113/ec5636b51016/ttj-23-3-257_f004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f7ab/9450113/2094d94c4e3b/ttj-23-3-257_f001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f7ab/9450113/fea09228a79a/ttj-23-3-257_f002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f7ab/9450113/bafbbbb12d17/ttj-23-3-257_f003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f7ab/9450113/ec5636b51016/ttj-23-3-257_f004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f7ab/9450113/2094d94c4e3b/ttj-23-3-257_f001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f7ab/9450113/fea09228a79a/ttj-23-3-257_f002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f7ab/9450113/bafbbbb12d17/ttj-23-3-257_f003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f7ab/9450113/ec5636b51016/ttj-23-3-257_f004.jpg

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Am J Case Rep. 2021 Mar 18;22:e927757. doi: 10.12659/AJCR.927757.
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Primary Melanoma of the Lung: A Systematic Review.原发性肺黑色素瘤:一项系统综述。
Medicina (Kaunas). 2020 Oct 30;56(11):576. doi: 10.3390/medicina56110576.
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Lung-only melanoma: UV mutational signature supports origin from occult cutaneous primaries and argues against the concept of primary pulmonary melanoma.
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Mod Pathol. 2020 Nov;33(11):2244-2255. doi: 10.1038/s41379-020-0594-0. Epub 2020 Jun 24.
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BMC Pulm Med. 2020 Apr 17;20(1):94. doi: 10.1186/s12890-020-1140-z.
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Primary pulmonary melanoma: An unexpected diagnosis.原发性肺黑色素瘤:一个意外的诊断。
Indian J Pathol Microbiol. 2018 Oct-Dec;61(4):636-638. doi: 10.4103/IJPM.IJPM_490_17.
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