Mass Spectrometry and Dioxin Analysis Laboratory, INRASTES, NCSR "Demokritos", 15341, Athens, Greece.
Laboratory of Environmental Chemistry, Department of Chemistry, National and Kapodistrian University of Athens, Panepistimiopolis, Athens, 15784, Greece.
Food Chem Toxicol. 2022 Jul;165:113087. doi: 10.1016/j.fct.2022.113087. Epub 2022 May 14.
Concentration levels of 26 polycyclic aromatic hydrocarbons and 20 trace elements were measured in dietary samples, in order to estimate the dietary intake and the potential exposure risk of the Greek population. Dietary samples were collected with the help of 30 volunteers inhabitants of Athens, Greece, according to the duplicate portion study (DPS) method where the determination of the compounds is conducted in the final consumed meal. DPS was selected as an alternative to a total diet study for its feasibility, low cost and realistic image that it provides. PAHs determination was performed by gas chromatography tandem mass spectrometry (GC-MS/MS) and trace elements determination by inductively coupled plasma mass spectrometry (ICP-MS). The estimated mean daily dietary exposure on 26 PAHs for an adult was estimated at 101.47 ng kg body weight day, while moderate to low exposure was related to the type and amount of food consumed. Exposure levels to PAHs do not indicate a possible risk for the health of the study group. For toxic, potentially essential and/or essential trace elements the daily exposure calculated for Greek population was in accordance with the reference values of the health-based guidances and compared to previous diet studies reported for the population of other countries was in general similar to the lower bound exposure.
为了估计希腊人口的饮食摄入量和潜在暴露风险，我们测量了饮食样本中 26 种多环芳烃和 20 种微量元素的浓度水平。饮食样本是在 30 名志愿者的帮助下收集的，这些志愿者是希腊雅典的居民，采用的是双份餐法（DPS），其中在最后一次食用的餐中对化合物进行测定。与全饮食研究相比，DPS 作为一种替代方法具有可行性、低成本和现实性，因此被选中。通过气相色谱串联质谱法（GC-MS/MS）测定多环芳烃，通过电感耦合等离子体质谱法（ICP-MS）测定微量元素。估计成年人每天通过饮食摄入 26 种多环芳烃的平均暴露量为 101.47ng/kg 体重，而暴露程度与食用的食物类型和数量有关。多环芳烃的暴露水平并不表明研究组的健康可能存在风险。对于有毒、潜在必需和/或必需的微量元素，为希腊人口计算的每日暴露量符合基于健康指南的参考值，与其他国家人口的先前饮食研究相比，总体上与较低的暴露量相似。
