Rosalind Franklin University Chicago Medical School, United States.
Wheaton College in Illinois, United States.
Crit Rev Oncol Hematol. 2022 Jul;175:103709. doi: 10.1016/j.critrevonc.2022.103709. Epub 2022 May 14.
Cancer survivors suffer from health deficits caused by their disease and treatment. This study conducted a systematic review and meta-analysis on how, and to what extent, cognitive-behavioral therapy (CBT) impacts functional health outcomes in cancer survivors.
We searched 7 electronic databases, 91 published review articles, and 4 professional websites for eligible randomized and non-randomized controlled trials focusing on cancer survivors.
We included 95 studies published between 1986 and 2021. Risk of bias across studies was low overall. We identified an overall statistically significant treatment effect size across functional health categories, d = 0.391, p < 0.001, and significant moderators associated with CBT's treatment effect, i.e., treatment phase and type of comparison.
CBT was effective at improving functional health outcomes of cancer survivors, regardless of therapy delivery modality or number of cancer diagnoses patients had, but not for newly diagnosed patients or those currently benefiting from an active comparator intervention.
癌症幸存者由于疾病和治疗而遭受健康缺陷。本研究对认知行为疗法（CBT）如何以及在何种程度上影响癌症幸存者的功能健康结果进行了系统回顾和荟萃分析。
我们搜索了 7 个电子数据库、91 篇已发表的综述文章和 4 个专业网站，以寻找针对癌症幸存者的合格随机和非随机对照试验。
我们纳入了 1986 年至 2021 年期间发表的 95 项研究。总体而言，研究之间的偏倚风险较低。我们确定了功能健康类别中整体具有统计学意义的治疗效果大小，d = 0.391，p < 0.001，以及与 CBT 治疗效果相关的显著调节因素，即治疗阶段和比较类型。
CBT 有效改善了癌症幸存者的功能健康结果，无论治疗方式或患者的癌症诊断数量如何，但对新诊断的患者或目前受益于主动对照干预的患者无效。
