认知行为疗法对癌症患者疲劳的影响：一项系统评价与荟萃分析
Effect of cognitive-behavioral therapy on fatigue in cancer patients: a systematic review and meta-analysis.
作者信息
Hosseini Koukamari Parisa, Karimy Mahmood, Ghaffari Mohtasham, Milajerdi Alireza
机构信息
Social Determinants of Health Research Center, Saveh University of Medical Sciences, Saveh, Iran.
School of Public Health and Safety, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
出版信息
Front Psychol. 2025 Jan 10;15:1435110. doi: 10.3389/fpsyg.2024.1435110. eCollection 2024.
BACKGROUND
Fatigue is a prevalent issue among cancer patients. Cognitive behavioral therapy (CBT) is an individualized intervention that empowers patients and caregivers to actively participate in the treatment process. A recent systematic review and meta-analysis examined the impact of CBT on fatigue in cancer patients.
METHODS
Articles published up to April 2023 were systematically searched in Scopus, PubMed, and the Web of Science using relevant keywords. All randomized clinical trials (RCTs) investigating the effects of CBT on fatigue in cancer patients were included. Statistical analyses were conducted using Stata version 14, with a significance level set at a -value of <0.05.
RESULTS
The current systematic review and meta-analysis encompasses 10 RCTs. CBT demonstrated a significant reduction in fatigue scores among cancer patients [standardized mean difference (WMD): -2.50; 95%CI: -3.43, -1.56; I2 = 95.8%, < 0.001]. This effect was consistent across all subgroup analyses.
CONCLUSION
This study underscores the significant impact of CBT on fatigue in cancer patients. Further randomized clinical trials focusing on various cancer types are warranted to validate and build upon these findings.
背景
疲劳是癌症患者中普遍存在的问题。认知行为疗法（CBT）是一种个体化干预措施，可使患者和护理人员积极参与治疗过程。最近一项系统评价和荟萃分析研究了CBT对癌症患者疲劳的影响。
方法
使用相关关键词在Scopus、PubMed和Web of Science中系统检索截至2023年4月发表的文章。纳入所有研究CBT对癌症患者疲劳影响的随机临床试验（RCT）。使用Stata 14版进行统计分析，显著性水平设定为P值<0.05。
结果
当前的系统评价和荟萃分析纳入了10项RCT。CBT显著降低了癌症患者的疲劳评分[标准化均数差（WMD）：-2.50；95%可信区间：-3.43，-1.56；I² = 95.8%，P < 0.001]。在所有亚组分析中，这种效果都是一致的。
结论
本研究强调了CBT对癌症患者疲劳的显著影响。有必要开展更多针对各种癌症类型的随机临床试验，以验证并拓展这些发现。
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