Shirinde Joyce, Wichmann Janine
School of Health Systems and Public Health, Faculty of Health Sciences, University of Pretoria, Pretoria, South Africa.
Int J Environ Health Res. 2023 Nov;33(11):1122-1131. doi: 10.1080/09603123.2022.2076813. Epub 2022 May 17.
The aim of this 10-year study was to investigate whether and how temperature modifies the association between daily ambient PM, NO SO air pollution and daily respiratory disease mortality in Cape Town. A time-stratified case-crossover epidemiological design was applied. Susceptibility by sex and age groups (15-64 years and ≥65 years) was also investigated. On days with medium Tapp levels, NO displayed a stronger association with respiratory mortality than PM or SO. Females appeared to be more susceptible to NO at medium Tapp levels to males. The 15-64-year-old age group seemed to be more vulnerable to NO and PM at medium Tapp levels compared to the elderly (≥65 years). At high Tapp levels, females were more susceptible to PM. The 15-64-year-old group were more vulnerable to NO and SO. The results can be used in present-day early warning systems and in risk assessments to estimate the impact of increased air pollution and temperature.
这项为期10年的研究旨在调查温度是否以及如何改变开普敦每日环境空气中的颗粒物（PM）、氮氧化物（NO）、二氧化硫（SO）空气污染与每日呼吸道疾病死亡率之间的关联。采用了时间分层病例交叉流行病学设计。还研究了按性别和年龄组（15 - 64岁和≥65岁）划分的易感性。在中等气温水平的日子里，NO与呼吸道死亡率的关联比PM或SO更强。在中等气温水平下，女性似乎比男性更容易受到NO的影响。与老年人（≥65岁）相比，15 - 64岁年龄组在中等气温水平下似乎更容易受到NO和PM的影响。在高气温度水平下，女性更容易受到PM的影响。15 - 64岁组更容易受到NO和SO的影响。这些结果可用于当今的早期预警系统和风险评估，以估计空气污染增加和温度升高的影响。
