Department of Stress Sciences and Psychosomatic Medicine, Graduate School of Medicine, The University of Tokyo, 7-3-1, Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan.
Department of Psychosomatic Medicine, Sunagawa City Medical Center, Sunagawa, Hokkaido, Japan.
Sci Rep. 2022 May 17;12(1):8247. doi: 10.1038/s41598-022-12318-x.
The usefulness of depression scales for patients with cancer based on item response theory (IRT) and computer adaptive testing (CAT) has not yet been fully explored. This study thus aimed to develop an IRT-based tool for measuring depression in patients with cancer. We analyzed data from 393 patients with cancer from four tertiary centers in Japan who had not received psychiatric treatment. They answered 62 questions across five categories regarding their psychiatric status over the previous week. We selected 28 items that satisfied the assumptions of IRT, fitted a graded response model to these items, and performed CAT simulations. The CAT simulation used an average of 6.96 items and showed a Pearson's correlation coefficient of 0.916 (95% confidence interval, 0.899-0.931) between the degree of depression estimated by simulation and that estimated using all 28 items. The measurement precision of CAT with only four items was superior to that of the estimation using the calibrated Patient Health Questionnaire-9. These results imply that this scale is useful and accurate for measuring depression in patients with cancer.
基于项目反应理论(IRT)和计算机自适应测试(CAT)的癌症患者抑郁量表的实用性尚未得到充分探索。因此,本研究旨在开发一种基于 IRT 的癌症患者抑郁测量工具。我们分析了来自日本四个三级中心的 393 名未经精神科治疗的癌症患者的数据。他们回答了关于过去一周精神状态的五类 62 个问题。我们选择了满足 IRT 假设的 28 个项目,将这些项目拟合到一个渐进式响应模型中,并进行了 CAT 模拟。CAT 模拟平均使用了 6.96 个项目,并且在通过模拟估计的抑郁程度与通过所有 28 个项目估计的抑郁程度之间显示出 0.916(95%置信区间,0.899-0.931)的 Pearson 相关系数。仅使用四个项目的 CAT 的测量精度优于使用校准后的患者健康问卷-9 进行的估计。这些结果表明,该量表对于测量癌症患者的抑郁是有用且准确的。