Nishida Jin, Kobayashi Motoyasu, Takahara Atsushi
JST, ERATO, Takahara Soft Interfaces Project, CE80, ‡Institute for Materials Chemistry and Engineering, §International Institute for Carbon-Neutral Energy Research (WPI-I2CNER), Kyushu University, 744 Motooka, Nishi-ku, Fukuoka 819-0395, Japan.
JST, ERATO, Takahara Soft Interfaces Project, CE80, Institute for Materials Chemistry and Engineering, §International Institute for Carbon-Neutral Energy Research (WPI-I2CNER), Kyushu University, 744 Motooka, Nishi-ku, Fukuoka 819-0395, Japan.
ACS Macro Lett. 2013 Feb 19;2(2):112-115. doi: 10.1021/mz300524q. Epub 2013 Jan 11.
An acrylamide-type copolymer containing hydroxyl, amino, and -nitrobenzyl protected catechol groups was synthesized as a functional mussel adhesive protein (MAP) mimetic. The resulting copolymer was stable even in the oxidative condition. Light irradiation to aqueous solution of the copolymer induced deprotection of a caged compound to give a native catechol group and triggered an oxidative cross-linking reaction to afford the adhesive gel. Two glass plates were adhered through light-activated gelation of the polymer solution in a humid air atmosphere. A novel type of light-activated adhesive with excellent stability and light controllable activation properties was successfully fabricated by modification of the MAP mimetic copolymer.
合成了一种含有羟基、氨基和对硝基苄基保护的儿茶酚基团的丙烯酰胺型共聚物，作为功能性贻贝粘附蛋白（MAP）模拟物。所得共聚物即使在氧化条件下也很稳定。对该共聚物水溶液进行光照射会引发笼形化合物的脱保护反应，生成天然儿茶酚基团，并引发氧化交联反应，从而得到粘附凝胶。在潮湿空气气氛中，通过聚合物溶液的光活化凝胶化将两块玻璃板粘合在一起。通过对MAP模拟共聚物进行改性，成功制备了一种具有优异稳定性和光可控活化性能的新型光活化粘合剂。
