脑胶质瘤幸存者的日常功能：与认知功能、心理因素和生活质量的关系。
Daily functioning in glioma survivors: associations with cognitive function, psychological factors and quality of life.
机构信息
Department of Psychiatry & Biobehavioral Sciences, Semel Institute for Neuroscience & Human Behavior, University of California Los Angeles, Los Angeles, CA 90024, USA.
Jonsson Comprehensive Cancer Center, University of California Los Angeles, Los Angeles, CA 90024, USA.
出版信息
CNS Oncol. 2022 Jun 1;11(2):CNS84. doi: 10.2217/cns-2022-0002. Epub 2022 May 18.
Understanding and supporting quality of life (QoL) and daily functioning in glioma patients is a clinical imperative. In this study, we examined the relationship between cognition, psychological factors, measures of health-related QoL and functioning in glioma survivors. We examined neuropsychological, self-reported cognition, mood and QoL correlates of work and non-work-related daily functioning in 23 glioma survivors, and carried out linear models of the best predictors. A total of 13/23 participants were working at the time of enrollment. The best model for worse work-related functioning (R = .83) included worse self-reported cognitive function, depression, loneliness and brain tumor symptoms. The best model for worse non-work-related functioning (R = .61) included worse self-reported cognitive functioning, anxiety, sleep disturbance and physical functioning. Neuropsychological variables were not among the most highly correlated with function. Worse cognitive, particularly self-reported and psychosocial outcomes may compromise optimal functioning in glioma survivors.
了解和支持胶质瘤患者的生活质量（QoL）和日常功能是临床的当务之急。在这项研究中，我们研究了认知、心理因素、与健康相关的生活质量和功能测量之间的关系在 23 名胶质瘤幸存者中，我们检查了与工作和非工作相关的日常功能相关的神经心理学、自我报告认知、情绪和生活质量，并进行了最佳预测因子的线性模型。在入组时，共有 13/23 名参与者正在工作。更差的工作相关功能（R=0.83）的最佳模型包括较差的自我报告认知功能、抑郁、孤独和脑瘤症状。更差的非工作相关功能（R=0.61）的最佳模型包括较差的自我报告认知功能、焦虑、睡眠障碍和身体功能。神经心理学变量并不是与功能相关性最高的变量之一。更差的认知，特别是自我报告和社会心理结果，可能会影响胶质瘤幸存者的最佳功能。
Zotero 插件