Westaby S, Parnell B, Pridie R B
J Cardiovasc Surg (Torino). 1987 Mar-Apr;28(2):124-7.
We studied the mode of presentation and results of surgery in 45 adults with coarctation of the aorta. Coarctation was unsuspected in 23 patients, 3 of whom presented with acute aortic dissection and 4 with severe aortic valve disease. Twenty seven were hypertensive before surgery. Three patients required emergency operation and all died. There was one death and one postoperative paraplegia amongst 39 patients who underwent elective operation. Of 21 preoperatively hypertensive patients studied at least 2 years after surgery blood pressure returned to normal levels in 10. Acute aortic dissection, aortic aneurysm formation and aortic valve disease complicate the surgical treatment of adult coarctation and hypertension may persist in as many as 50% of patients. Nevertheless surgery is preferable to the poor reported results of long term medical management.
我们研究了45例成人主动脉缩窄患者的临床表现方式及手术结果。23例患者术前未被怀疑有主动脉缩窄,其中3例出现急性主动脉夹层,4例伴有严重主动脉瓣疾病。27例患者术前有高血压。3例患者需要急诊手术,均死亡。在接受择期手术的39例患者中,有1例死亡,1例术后发生截瘫。在21例术前有高血压的患者中,术后至少2年进行研究,其中10例血压恢复到正常水平。急性主动脉夹层、主动脉瘤形成和主动脉瓣疾病使成人主动脉缩窄的外科治疗复杂化,多达50%的患者高血压可能持续存在。然而,与长期药物治疗报道的不良结果相比,手术治疗更为可取。