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2022 年肥胖症流行病学更新及行动呼吁:随着其孪生 COVID-19 大流行似乎正在消退,肥胖和代谢功能紊乱大流行仍在肆虐。

A 2022 update on the epidemiology of obesity and a call to action: as its twin COVID-19 pandemic appears to be receding, the obesity and dysmetabolism pandemic continues to rage on.

机构信息

Department of Medicine, Boston VA Healthcare system and Beth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Ave, Slosberg-Landay SL-419, Boston, MA 02215, USA.

Department of Medicine, Boston VA Healthcare system and Beth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Ave, Slosberg-Landay SL-419, Boston, MA 02215, USA.

出版信息

Metabolism. 2022 Aug;133:155217. doi: 10.1016/j.metabol.2022.155217. Epub 2022 May 15.

DOI:10.1016/j.metabol.2022.155217
PMID:35584732
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9107388/
Abstract

The WHO just released in May 2022 a report on the state of the obesity pandemic in Europe, stating that 60% of citizens in the area of Europe are either overweight or obese, and highlighting the implications of the obesity pandemic, especially as it interacts with the COVID pandemic to create a twin pandemic, to increase morbidity and mortality. Obesity is a complex disease which has reached pandemic dimensions. The worldwide prevalence of obesity has nearly tripled since 1975, mainly due to the adoption of a progressively more sedentary lifestyle and the consumption of less healthy diets. We first report herein updated prevalence rates of overweight and obesity by sex, age, and region first in Europe, per the WHO report, and then worldwide between 1980 and 2019, as we analyze and present herein the data provided by the Global Burden of Disease Study. The prevalence of obesity is higher in women than in men of any age and the prevalence of both overweight and obesity increases with age and has reached their highest point between the ages of 50 to 65 years showing a slight downward trend afterwards. The age-standardized prevalence of obesity has increased from 4.6% in 1980 to 14.0% in 2019. The American and European region have the highest obesity prevalence and the USA and Russia are the countries with the most obese residents. Given dire implications in terms of comorbidities and mortality, these updated epidemiological findings call for coordinated actions from local and regional governments, the scientific community and individual patients alike, as well as the food industry for the obesity pandemic to be controlled and alleviated. We can hopefully learn from the COVID-19 pandemic, where collaborative efforts worldwide, focused intense work at both the local and global level and well-coordinated leadership have demonstrated that humankind is capable of amazing accomplishments by leveraging science and public health, and that we can finally make strides in terms of understanding and combating the obesity pandemic and its dire comorbidities including diabetes, NAFLD, CVD and obesity associated malignancies.

摘要

世界卫生组织(WHO)于 2022 年 5 月发布了一份关于欧洲肥胖大流行状况的报告,指出欧洲地区有 60%的公民超重或肥胖,并强调了肥胖大流行的影响,特别是它与 COVID-19 大流行相互作用,形成双重大流行,从而增加发病率和死亡率。肥胖是一种复杂的疾病,已经达到了大流行的程度。自 1975 年以来,全球肥胖的患病率几乎增加了两倍,主要是由于生活方式日益久坐和饮食习惯不健康导致的。我们首先根据世界卫生组织的报告,在欧洲报告了按性别、年龄和地区划分的超重和肥胖的最新流行率,然后分析并呈现了全球 1980 年至 2019 年的数据,这些数据来自全球疾病负担研究。无论任何年龄,女性的肥胖患病率都高于男性,超重和肥胖的患病率都随着年龄的增长而增加,并在 50 至 65 岁之间达到最高水平,此后略有下降。肥胖的年龄标准化患病率从 1980 年的 4.6%上升到 2019 年的 14.0%。美洲和欧洲地区的肥胖患病率最高,美国和俄罗斯是肥胖人口最多的国家。鉴于肥胖与多种疾病和死亡率之间的严重关系,这些最新的流行病学发现呼吁地方和地区政府、科学界和患者个人以及食品行业采取协调行动,以控制和缓解肥胖大流行。我们可以从 COVID-19 大流行中吸取教训,全世界的合作努力,在地方和全球层面集中开展密集工作,并进行良好协调的领导,证明人类有能力通过利用科学和公共卫生取得惊人的成就,我们最终可以在理解和应对肥胖大流行及其包括糖尿病、非酒精性脂肪性肝病、心血管疾病和肥胖相关恶性肿瘤在内的严重合并症方面取得进展。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/95bc/9107388/fb5f6408c75d/gr4_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/95bc/9107388/635daf843d8a/gr1_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/95bc/9107388/875d2cc50de8/gr2_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/95bc/9107388/be9fc5dd7e6a/gr3_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/95bc/9107388/fb5f6408c75d/gr4_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/95bc/9107388/635daf843d8a/gr1_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/95bc/9107388/875d2cc50de8/gr2_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/95bc/9107388/be9fc5dd7e6a/gr3_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/95bc/9107388/fb5f6408c75d/gr4_lrg.jpg

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