在TDP-43型肌萎缩侧索硬化症小鼠模型中，神经丝轻链（NF-L）水平升高，与肌萎缩侧索硬化症患者的NF-L水平相似。 - Suppr

Increased NF-L levels in the TDP-43 ALS mouse model resemble NF-L levels in ALS patients.

作者信息

Buck Eva, Oeckl Patrick, Grozdanov Veselin, Bopp Verena, Kühlwein Julia K, Ruf Wolfgang P, Wiesner Diana, Roselli Francesco, Weishaupt Jochen H, Ludolph Albert C, Otto Markus, Danzer Karin M

机构信息

German Center for Neurodegenerative Diseases (DZNE), Ulm, Germany.

Neurology, University Clinic, University of Ulm, Ulm, Germany.

出版信息

Acta Neuropathol. 2022 Jul;144(1):161-164. doi: 10.1007/s00401-022-02436-1. Epub 2022 May 18.

DOI:10.1007/s00401-022-02436-1

PMID:35585288

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9217825/

Abstract

摘要

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed95/9217825/86e36a717314/401_2022_2436_Fig1_HTML.jpg

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Increased NF-L levels in the TDP-43 ALS mouse model resemble NF-L levels in ALS patients.

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Increased NF-L levels in the TDP-43 ALS mouse model resemble NF-L levels in ALS patients.

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