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慢性炎症性脱髓鞘性多发性神经病:一例具有非典型特征的独特慢性病病例。

Chronic inflammatory demyelinating polyneuropathy: A unique case of chronic disease with atypical features.

作者信息

Christie Omari, Mirchia Kavya, Mangla Rajiv, Hussain Ali, Hussien Abdelmohsen Radwan

机构信息

SUNY Upstate Medical University, 750 E Adams Street, Syracuse, NY 13210, USA.

University of Rochester, 601 Elmwood Avenue, Rochester, NY 14624, USA.

出版信息

Radiol Case Rep. 2022 May 9;17(7):2441-2447. doi: 10.1016/j.radcr.2022.03.029. eCollection 2022 Jul.

Abstract

We present a unique case of diffusely extensive Chronic Inflammatory Demyelinating Polyneuropathy (CIDP). Typically affecting the peripheral nervous system and manifesting with muscle weakness, breakdown or paresthesia, we present a case that additionally demonstrates; cranial nerve involvement, central nervous system parenchymal lesions, and chronic osseous remodeling of the nerve tracts. Cranial nerve involvement to this extent has only been described in one other case report to our knowledge. Central nervous system parenchymal lesions are extremely rare in CIDP and no discrete discussion about osseous remodeling has been presented, thus far, in the literature. The findings illustrated in this case may spur further understanding of imaging characteristics most associated with chronic CIDP disease and care measures that could help stratify patients most at risk for severe symptomologies.

摘要

我们报告了一例独特的弥漫性广泛性慢性炎症性脱髓鞘性多发性神经病(CIDP)病例。CIDP通常累及周围神经系统,表现为肌肉无力、功能障碍或感觉异常,而我们所报告的这例病例还表现出;颅神经受累、中枢神经系统实质病变以及神经束的慢性骨质重塑。据我们所知,如此程度的颅神经受累仅在另一例病例报告中有所描述。中枢神经系统实质病变在CIDP中极为罕见,并且迄今为止,文献中尚未有关于骨质重塑的具体讨论。该病例所展示的发现可能会促进对与慢性CIDP疾病最相关的影像学特征以及有助于对最易出现严重症状的患者进行分层的护理措施的进一步理解。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3e32/9108731/fd90caf0a421/gr1.jpg

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