Edmonson Alexis, Iwanaga Joe, Olewnik Łukasz, Dumont Aaron S, Tubbs R Shane
Department of Structural & Cellular Biology, Tulane University School of Medicine, New Orleans, LA, USA.
Department of Neurosurgery, Tulane Center for Clinical Neurosciences, Tulane University School of Medicine, New Orleans, LA, USA.
Anat Cell Biol. 2022 Jun 30;55(2):113-117. doi: 10.5115/acb.21.032. Epub 2022 May 19.
The tensor tympani muscle is structurally important in the middle ear, specifically through its involvement in the impedance of sound in response to intense auditory and non-auditory stimuli. Despite numerous studies, its true function has been debated for many years; questions still remain about its role in auditory and non-auditory reflexes and in sound damping. Some studies suggest that the tensor tympani muscle contracts as a result of non-auditory stimulation such as facial or head movements; others suggest that it contracts due to input from the cochlear nucleus, therefore by way of auditory stimulation. Whatever the cause, contraction of the tensor tympani muscle results in low frequency mixed hearing loss, either to protect the inner ear from loud sounds or to desensitize the ear to self-generated sounds. A review of these studies indicated that the tensor tympani muscle has a wide range of functions, yet the mechanisms of some of them have not been clearly demonstrated. One major question is whether the tensor tympani muscle contributes to sound damping; and if it does, what specific role it serves. The primary purpose of this review article is to explore the functions of the tensor tympani muscle in light of recent research advances.
鼓膜张肌在中耳的结构中具有重要作用,特别是通过参与对强烈听觉和非听觉刺激的声音阻抗来实现。尽管有大量研究,但多年来其真正功能一直存在争议;关于它在听觉和非听觉反射以及声音阻尼中的作用仍存在疑问。一些研究表明,鼓膜张肌因面部或头部运动等非听觉刺激而收缩;另一些研究则表明,它是由于来自蜗神经核的输入,即通过听觉刺激而收缩。无论原因如何,鼓膜张肌的收缩都会导致低频混合性听力损失,要么是为了保护内耳免受大声响的伤害,要么是使耳朵对自身产生的声音不敏感。对这些研究的综述表明,鼓膜张肌具有广泛的功能,但其一些功能的机制尚未得到明确证实。一个主要问题是鼓膜张肌是否有助于声音阻尼;如果是,它发挥了什么具体作用。这篇综述文章的主要目的是根据最近的研究进展探讨鼓膜张肌的功能。