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咬肌前庭诱发肌源性电位:一种评估前庭咬肌反射通路的新工具。

Masseter Vestibular evoked myogenic potentials: A new tool to assess the vestibulomasseteric reflex pathway.

作者信息

Nagarajan Aishwarya, Sinha Sujeet Kumar

机构信息

Department of Audiology, AIISH, Mysore, 06, India.

出版信息

J Otol. 2024 Jan;19(1):46-54. doi: 10.1016/j.joto.2023.12.005. Epub 2023 Dec 29.

Abstract

PURPOSE

This review article provides the readers with an in-depth insight in understanding and interpreting various research literatures on the masseter vestibular evoked myogenic potentials (mVEMP). The article also reviews the contemporary researches involving the clinical applications of the mVEMP.

CONCLUSIONS

Masseter VEMP is an evolving yet clinically promising neuro-otology test tool that has recently gained more research interest and is considered an additional tool to diagnose various vestibular disorders. Masseter VEMP assesses the functional integrity of the acoustic-masseteric and vestibulo-masseteric reflex pathways. The mVEMP could be used as a complementary test to evaluate the same peripheral generator as the cervical VEMP but a different central pathway i.e., vestibulo-trigeminal pathway. Various research studies that have experimented on parameters such as the effect of different electrode montages (zygomatic vs mandibular configurations), stimulation rates, filter settings and stimuli used to evoke mVEMP have been discussed in this article that could assist in the optimization of a comprehensive clinical protocol. The latency and the amplitude of mVEMP waveforms serve as significant parameters in differentiating normals from those of the clinical populations. Along with the cVEMPs and oVEMPs, mVEMP might help diagnose brainstem lesions in REM Sleep behaviour disorders, Multiple Sclerosis and Parkinson's disease. However, further studies are required to probe in this area of research.

摘要

目的

这篇综述文章为读者深入理解和解读有关咬肌前庭诱发肌源性电位(mVEMP)的各种研究文献提供了见解。本文还回顾了涉及mVEMP临床应用的当代研究。

结论

咬肌VEMP是一种不断发展但在临床上颇具前景的神经耳科学测试工具,最近受到了更多的研究关注,并被视为诊断各种前庭疾病的辅助工具。咬肌VEMP评估听-咬肌和前庭-咬肌反射通路的功能完整性。mVEMP可作为一种补充测试,用于评估与颈肌VEMP相同的外周发生器,但评估的是不同的中枢通路,即前庭-三叉神经通路。本文讨论了各种关于不同电极组合(颧部与下颌部配置)、刺激率、滤波设置以及用于诱发mVEMP的刺激等参数的研究,这些研究有助于优化全面的临床方案。mVEMP波形的潜伏期和波幅是区分正常人与临床人群的重要参数。与颈肌VEMP和眼肌VEMP一起,mVEMP可能有助于诊断快速眼动睡眠行为障碍、多发性硬化症和帕金森病中的脑干病变。然而,该研究领域还需要进一步的研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4441/10837556/8236654a90d8/gr1.jpg

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