Universidade Federal do Piauí, Centro de Ciências da Saúde, Teresina, PI, Brasil.
Universidade Estadual do Piauí, Centro de Ciências da Saúde, Teresina, PI, Brasil.
Epidemiol Serv Saude. 2022 Apr 27;31(1):e2021339. doi: 10.1590/S1679-49742022000100013. eCollection 2022.
To analyze epidemiological and operational indicators, the temporal trend and spatial distribution of visceral leishmaniasis (VL), as well as VL-HIV co-infection in the state of Piauí, Brazil, from 2007 to 2019.
This was an ecological time series study. Prais-Winsten regression was used to analyze the trend of VL incidence, case fatality ratio and operational indicators.
Mean VL incidence in the state was 6.03/100,000 inhabitants, with a rising trend in the 40-59 age group [annual percent change (APC) = 3.88; 95%CI 0.49;7.40] and in the regions located in the south of the state: Tabuleiros do Alto Parnaíba (APC = 14.19; 95%CI 3.91;25.50) and Chapada das Mangabeiras (APC = 12.15; 95%CI 6.69;24.96). Mean case fatality ratio was 6.02% and it remained stable. The mean rate of progression to cure was 52.58%, with a falling trend (APC = -5.67; 95%CI -8.05; -3.23).
There was rising trend in VL incidence and a falling trend in its cure rate.
分析巴西皮奥伊州 2007 年至 2019 年内脏利什曼病（VL）的流行病学和操作指标、时间趋势和空间分布，以及 VL-HIV 合并感染情况。
这是一项生态时间序列研究。采用普赖斯-温斯坦回归分析 VL 发病率、病死率和操作指标的趋势。
该州 VL 发病率的平均值为 6.03/100,000 居民，40-59 岁年龄组呈上升趋势[年变化率（APC）=3.88；95%可信区间（95%CI）0.49；7.40]，位于该州南部的塔布卢罗斯-阿尔托-帕纳伊巴（Tabuleiros do Alto Parnaíba）和查帕达-达斯-曼加贝iras（Chapada das Mangabeiras）地区的发病率也呈上升趋势（APC=14.19；95%CI 3.91；25.50）和 APC=12.15；95%CI 6.69；24.96）。平均病死率为 6.02%，保持稳定。进展到治愈的平均比例为 52.58%，呈下降趋势（APC=-5.67；95%CI-8.05；-3.23）。
VL 发病率呈上升趋势，治愈率呈下降趋势。
