Dipartimento di Chimica e Biologia "Adolfo Zambelli", Università degli Studi di Salerno, Via Giovanni Paolo II, 132, 84084 Fisciano, Italy.
Sensors (Basel). 2022 Apr 21;22(9):3173. doi: 10.3390/s22093173.
In this work, the authors explored the interaction of a suite of fluorescent zinc complexes with HS. The authors provide evidence that HS binds the zinc center of all the complexes under investigation, allowing them to possibly function as sensors by a 'coordinative-based' approach. Naked-eye color changes occur when treating the systems with HS, so the fluorescence responses are modulated by the presence of HS, which has been related to a change in the energy level and coupling of excited states through a computational study. The results show the potential of the systems to function as HS/HS colorimetric and fluorescent sensors. Paper-strip-based sensing experiments foresee the potential of using this family of complexes as chemosensors of HS in more complex biological fluids.
在这项工作中，作者研究了一系列荧光锌配合物与 HS 的相互作用。作者提供的证据表明，HS 与所有被研究的配合物的锌中心结合，使它们能够通过“基于配位的”方法作为传感器发挥作用。当用 HS 处理这些体系时，会发生肉眼可见的颜色变化，因此荧光响应被 HS 的存在调制，这通过计算研究与激发态能级和耦合的变化有关。研究结果表明，这些体系具有作为 HS/HS 比色和荧光传感器的潜力。基于纸条的传感实验预示着该系列配合物作为更复杂生物流体中 HS 的化学传感器的潜在用途。
