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50mm 焦距柱面光学线扫描光学相干断层成像线性波数谱仪设计。

Design of a Linear Wavenumber Spectrometer for Line Scanning Optical Coherence Tomography with 50 mm Focal Length Cylindrical Optics.

机构信息

Department of Mechanical, Industrial and Aerospace Engineering (MIAE), Concordia University, Montreal, QC H3G 1M8, Canada.

Seurat Technologies Inc., 70 Chestnut st, Andover, MA 01810, USA.

出版信息

Sensors (Basel). 2022 Apr 25;22(9):3278. doi: 10.3390/s22093278.

DOI:10.3390/s22093278
PMID:35590968
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9104028/
Abstract

Optical coherence tomography (OCT) has a wide range of uses in bioimaging and nondestructive testing. Larger bandwidth light sources have recently been implemented to enhance measurement resolution. Increased bandwidth has a negative impact on spectral nonlinearity in k space, notably in the case of spectral domain OCT (SD-OCT). This nonlinearity reduces the depth-dependent signal sensitivity of the spectrometers. A grating and prism combination is extensively used for linearizing. In an earlier study, we used a combination of the reflective grating and prism, as well as a cylindrical mirror with a radius of 180 mm, to achieve a high SR ratio with low nonlinearity. A creative design for a spectrometer with a cylindrical mirror of radius 50 mm, a light source with a center wavelength of 830 ± 100 nm (μm - 6.756 μm in k-space), and a grating of 1600 lines/mm is presented in this work. The design optimization is performed using MATLAB and ZEMAX. In the proposed design, the nonlinearity error reduced from 157∘× μm to 10.75∘× μm within the wavenumber range considered. The sensitivity research revealed that, with the new design, the SR ratio is extremely sensitive to the imaging optics' angles. To resolve this, a spectrometer based on Grism is introduced. We present a Grism-based spectrometer with an optimized SR ratio of 0.97 and nonlinearity of 0.792∘× μm (Δθ/Δk). According to the sensitivity study, the Grism-based spectrometer is more robust.

摘要

光学相干断层扫描(OCT)在生物成像和无损检测中有广泛的应用。最近,更大带宽的光源被用于提高测量分辨率。增加带宽对 k 空间中的光谱非线性有负面影响,尤其是在光谱域 OCT(SD-OCT)的情况下。这种非线性降低了光谱仪的深度相关信号灵敏度。光栅和棱镜组合被广泛用于线性化。在早期的研究中,我们使用了反射光栅和棱镜的组合,以及半径为 180mm 的圆柱镜,以实现高 SR 比和低非线性。本文提出了一种具有半径为 50mm 的圆柱镜、中心波长为 830±100nm(μm-6.756μm 在 k 空间)的光源和 1600 线/mm 光栅的光谱仪的创造性设计。使用 MATLAB 和 ZEMAX 进行设计优化。在提出的设计中,在所考虑的波数范围内,非线性误差从 157∘×μm 降低到 10.75∘×μm。灵敏度研究表明,在新设计中,SR 比对成像光学角度极其敏感。为了解决这个问题,我们引入了基于 Grism 的光谱仪。我们提出了一种基于 Grism 的光谱仪,其优化的 SR 比为 0.97,非线性为 0.792∘×μm(Δθ/Δk)。根据灵敏度研究,基于 Grism 的光谱仪更稳健。

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本文引用的文献

1
Design and Optimization of a Linear Wavenumber Spectrometer with Cylindrical Optics for Line Scanning Optical Coherence Tomography.设计并优化了一种采用柱面光学元件的线扫光学相干层析成像线性光谱仪。
Sensors (Basel). 2021 Sep 28;21(19):6463. doi: 10.3390/s21196463.
2
Line-Field Optical Coherence Tomography as a tool for In vitro characterization of corneal biomechanics under physiological pressures.线阵光学相干断层扫描作为一种在生理压力下对角膜生物力学进行体外特征描述的工具。
Sci Rep. 2019 Apr 19;9(1):6321. doi: 10.1038/s41598-019-42789-4.
3
Ultrahigh resolution retinal imaging by visible light OCT with longitudinal achromatization.
通过具有纵向消色差功能的可见光光学相干断层扫描实现超高分辨率视网膜成像。
Biomed Opt Express. 2018 Mar 5;9(4):1477-1491. doi: 10.1364/BOE.9.001477. eCollection 2018 Apr 1.
4
Design and implementation of a low-cost, portable OCT system.一种低成本便携式光学相干断层扫描(OCT)系统的设计与实现。
Biomed Opt Express. 2018 Feb 20;9(3):1232-1243. doi: 10.1364/BOE.9.001232. eCollection 2018 Mar 1.
5
High resolution corneal and single pulse imaging with line field spectral domain optical coherence tomography.利用线场光谱域光学相干断层扫描技术进行高分辨率角膜和单脉冲成像。
Opt Express. 2016 May 30;24(11):12395-405. doi: 10.1364/OE.24.012395.
6
Continuing the success of Biomedical Optics Express: editorial.延续《生物医学光学快报》的成功:社论
Biomed Opt Express. 2016 Jan 11;7(2):420-1. doi: 10.1364/BOE.7.000420. eCollection 2016 Feb 1.
7
Micro-optical coherence tomography tracking of magnetic gene transfection via Au-Fe3O4 dumbbell nanoparticles.基于 Au-Fe3O4 哑铃型纳米粒子的磁基因转染的微光学相干断层扫描追踪。
Nanoscale. 2015 Nov 7;7(41):17249-53. doi: 10.1039/c5nr05459a.
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High-resolution 1050 nm spectral domain retinal optical coherence tomography at 120 kHz A-scan rate with 6.1 mm imaging depth.120千赫A扫描速率、成像深度为6.1毫米的高分辨率1050纳米光谱域视网膜光学相干断层扫描技术。
Biomed Opt Express. 2013 Feb 1;4(2):245-59. doi: 10.1364/BOE.4.000245. Epub 2013 Jan 16.
9
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