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50mm 焦距柱面光学线扫描光学相干断层成像线性波数谱仪设计。

Design of a Linear Wavenumber Spectrometer for Line Scanning Optical Coherence Tomography with 50 mm Focal Length Cylindrical Optics.

机构信息

Department of Mechanical, Industrial and Aerospace Engineering (MIAE), Concordia University, Montreal, QC H3G 1M8, Canada.

Seurat Technologies Inc., 70 Chestnut st, Andover, MA 01810, USA.

出版信息

Sensors (Basel). 2022 Apr 25;22(9):3278. doi: 10.3390/s22093278.

Abstract

Optical coherence tomography (OCT) has a wide range of uses in bioimaging and nondestructive testing. Larger bandwidth light sources have recently been implemented to enhance measurement resolution. Increased bandwidth has a negative impact on spectral nonlinearity in k space, notably in the case of spectral domain OCT (SD-OCT). This nonlinearity reduces the depth-dependent signal sensitivity of the spectrometers. A grating and prism combination is extensively used for linearizing. In an earlier study, we used a combination of the reflective grating and prism, as well as a cylindrical mirror with a radius of 180 mm, to achieve a high SR ratio with low nonlinearity. A creative design for a spectrometer with a cylindrical mirror of radius 50 mm, a light source with a center wavelength of 830 ± 100 nm (μm - 6.756 μm in k-space), and a grating of 1600 lines/mm is presented in this work. The design optimization is performed using MATLAB and ZEMAX. In the proposed design, the nonlinearity error reduced from 157∘× μm to 10.75∘× μm within the wavenumber range considered. The sensitivity research revealed that, with the new design, the SR ratio is extremely sensitive to the imaging optics' angles. To resolve this, a spectrometer based on Grism is introduced. We present a Grism-based spectrometer with an optimized SR ratio of 0.97 and nonlinearity of 0.792∘× μm (Δθ/Δk). According to the sensitivity study, the Grism-based spectrometer is more robust.

摘要

光学相干断层扫描(OCT)在生物成像和无损检测中有广泛的应用。最近,更大带宽的光源被用于提高测量分辨率。增加带宽对 k 空间中的光谱非线性有负面影响,尤其是在光谱域 OCT(SD-OCT)的情况下。这种非线性降低了光谱仪的深度相关信号灵敏度。光栅和棱镜组合被广泛用于线性化。在早期的研究中,我们使用了反射光栅和棱镜的组合,以及半径为 180mm 的圆柱镜,以实现高 SR 比和低非线性。本文提出了一种具有半径为 50mm 的圆柱镜、中心波长为 830±100nm(μm-6.756μm 在 k 空间)的光源和 1600 线/mm 光栅的光谱仪的创造性设计。使用 MATLAB 和 ZEMAX 进行设计优化。在提出的设计中,在所考虑的波数范围内,非线性误差从 157∘×μm 降低到 10.75∘×μm。灵敏度研究表明,在新设计中,SR 比对成像光学角度极其敏感。为了解决这个问题,我们引入了基于 Grism 的光谱仪。我们提出了一种基于 Grism 的光谱仪,其优化的 SR 比为 0.97,非线性为 0.792∘×μm(Δθ/Δk)。根据灵敏度研究,基于 Grism 的光谱仪更稳健。

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