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一名持续非卧床腹膜透析患者由[具体病因未给出]引起的细菌性腹膜炎 。

Bacterial Peritonitis Caused by in a Patient Undergoing Continuous Ambulatory Peritoneal Dialysis.

作者信息

Tang Ling, Huang Ying, Li Tingting, Li Yajuan, Xu Yuanhong

机构信息

Department of Clinical Laboratory, First Affiliated Hospital of Anhui Medical University, Hefei, People's Republic of China.

出版信息

Infect Drug Resist. 2022 May 12;15:2475-2480. doi: 10.2147/IDR.S364626. eCollection 2022.

Abstract

BACKGROUND

is an environmental saprophyte that potentially causes various infections in humans. It has been reported to cause rare opportunistic infections in immunocompromised patients or patients with indwelling foreign bodies.

CASE PRESENTATION

We report a case of continuous ambulatory peritoneal dialysis (CAPD)-related peritonitis caused by (). The patient was admitted to our hospital while demonstrating a cloudy peritoneal dialysate. Peritoneal fluid sample culturing yielded yellow-greyish, dry and membrane-like colonies. Gram staining showed straight, gram-positive rods. The organism was identified to be species by matrix-assisted laser desorption/ionization-time of flight mass spectrometry (MALDI-TOF MS). It was then characterized to be homologous to in the GenBank database by 16S Ribosomal RNA Sequencing. The strain was susceptible to quinolones, carbapenems and linezolid, but intermediately resistant to vancomycin in drug susceptibility testing. Eventually, the peritonitis was controlled with meropenem and the patient discharged from the hospital.

CONCLUSION

Here, we describe the first case of CAPD-related peritonitis caused by in China. Importantly, show resistance to cephalosporins and heterogeneous resistance to vancomycin, guideline-based empiric therapy occasionally fails. Further analyses of similar cases are required to understand the characteristics and formulate appropriate therapy regimen for infections.

摘要

背景

[具体细菌名称]是一种环境腐生菌,可能导致人类多种感染。据报道,它可在免疫功能低下患者或留置异物的患者中引起罕见的机会性感染。

病例报告

我们报告一例由[具体细菌名称]引起的持续性非卧床腹膜透析(CAPD)相关性腹膜炎病例。患者因腹膜透析液浑浊入住我院。腹膜液样本培养产生黄灰色、干燥且呈膜状的菌落。革兰氏染色显示为直的革兰氏阳性杆菌。通过基质辅助激光解吸电离飞行时间质谱(MALDI-TOF MS)鉴定该菌为[具体细菌名称]种。然后通过16S核糖体RNA测序确定其在GenBank数据库中与[具体细菌名称]同源。在药敏试验中,该菌株对喹诺酮类、碳青霉烯类和利奈唑胺敏感,但对万古霉素呈中度耐药。最终,美罗培南控制了腹膜炎,患者出院。

结论

在此,我们描述了中国首例由[具体细菌名称]引起的CAPD相关性腹膜炎病例。重要的是,[具体细菌名称]对头孢菌素耐药且对万古霉素存在异质性耐药,基于指南的经验性治疗偶尔会失败。需要对类似病例进行进一步分析,以了解其特征并制定针对[具体细菌名称]感染的合适治疗方案。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/faee/9113660/d5ffd0d3512a/IDR-15-2475-g0002.jpg

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