Chen Chang-Hung, Lee Chao-Tai, Chang Tsung-Chain
Department of Internal Medicine, Chest Division, Tainan Municipal Hospital, Tainan, Taiwan.
Department of Clinical Laboratory, Tainan Municipal Hospital, Tainan, Taiwan.
Springerplus. 2016 Nov 29;5(1):2033. doi: 10.1186/s40064-016-3707-y. eCollection 2016.
We describe an immunocompromised patient with bacteremia and coinfection of pneumonia.
A 75-year-old male was admitted to our hospital complaining of persistent fever with general malaise. His medical history showed that he had diabetes mellitus (HbA1C 9.2%). A chest computed tomography (CT) showed left upper lung consolidation . Two sets of blood culture at admission finally showed . Moreover, three transbronchoscopy washing specimen cultures revealed .
The organism was identified using conventional biochemical identification methods, PCR-restriction DNA fragment analysis, and 16S rRNA gene sequencing. The clinical mycobacterial isolates were identified to the species level by combining Polymerase Chain Reaction (PCR) with an oligonucleotide microarray to detect the amplicons.
According to our literature review, our patient's case was the first of a coinfection with and . Prolonged antibiotic treatment and underlying disease control are necessary for this type of patient.
我们描述了一例患有菌血症和肺炎合并感染的免疫功能低下患者。
一名75岁男性因持续发热伴全身不适入院。他的病史显示患有糖尿病（糖化血红蛋白9.2%）。胸部计算机断层扫描（CT）显示左上肺实变。入院时两组血培养最终显示……此外，三次经支气管镜灌洗标本培养显示……
使用传统生化鉴定方法、PCR限制性DNA片段分析和16S rRNA基因测序对该微生物进行鉴定。通过聚合酶链反应（PCR）与寡核苷酸微阵列相结合以检测扩增子，将临床分枝杆菌分离株鉴定到种水平。
根据我们的文献综述，我们患者的病例是首例……和……合并感染。对于这类患者，延长抗生素治疗和控制基础疾病是必要的。
