• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

相似文献

1
Fission Impossible: Stabilized miRNA-Based Analogs in Neurodegenerative Disease.不可能的裂变：神经退行性疾病中基于微小RNA的稳定类似物
Front Neurosci. 2022 May 3;16:875957. doi: 10.3389/fnins.2022.875957. eCollection 2022.
2
microRNA-146a Signaling in Alzheimer's Disease (AD) and Prion Disease (PrD).微小RNA-146a在阿尔茨海默病（AD）和朊病毒病（PrD）中的信号传导
Front Neurol. 2020 Jun 25;11:462. doi: 10.3389/fneur.2020.00462. eCollection 2020.
3
MicroRNA-146a represses LRP2 translation and leads to cell apoptosis in Alzheimer's disease.微小RNA-146a抑制低密度脂蛋白受体相关蛋白2的翻译并导致阿尔茨海默病中的细胞凋亡。
FEBS Lett. 2016 Jul;590(14):2190-200. doi: 10.1002/1873-3468.12229. Epub 2016 Jul 8.
4
Addressing Alzheimer's Disease (AD) Neuropathology Using Anti-microRNA (AM) Strategies.采用抗 microRNA (AM) 策略解决阿尔茨海默病 (AD) 神经病理学问题。
Mol Neurobiol. 2019 Dec;56(12):8101-8108. doi: 10.1007/s12035-019-1632-0. Epub 2019 Jun 10.
5
Lipopolysaccharide-stimulated, NF-kB-, miRNA-146a- and miRNA-155-mediated molecular-genetic communication between the human gastrointestinal tract microbiome and the brain.脂多糖刺激的、NF-kB-、miRNA-146a-和 miRNA-155-介导的人类胃肠道微生物组与大脑之间的分子遗传学通讯。
Folia Neuropathol. 2019;57(3):211-219. doi: 10.5114/fn.2019.88449.
6
NF-kB (p50/p65)-Mediated Pro-Inflammatory microRNA (miRNA) Signaling in Alzheimer's Disease (AD).核因子-κB（p50/p65）介导的阿尔茨海默病（AD）中的促炎微小RNA（miRNA）信号传导
Front Mol Neurosci. 2022 Jun 28;15:943492. doi: 10.3389/fnmol.2022.943492. eCollection 2022.
7
microRNA-146a-5p, Neurotropic Viral Infection and Prion Disease (PrD).微小 RNA-146a-5p、神经亲和性病毒感染与朊病毒病（PrD）。
Int J Mol Sci. 2021 Aug 25;22(17):9198. doi: 10.3390/ijms22179198.
8
miR-146a Plasma Levels Are Not Altered in Alzheimer's Disease but Correlate With Age and Illness Severity.阿尔茨海默病患者血浆中miR-146a水平未发生改变，但与年龄和疾病严重程度相关。
Front Aging Neurosci. 2020 Jan 17;11:366. doi: 10.3389/fnagi.2019.00366. eCollection 2019.
9
MicroRNA (miRNA) Signaling in the Human CNS in Sporadic Alzheimer's Disease (AD)-Novel and Unique Pathological Features.散发性阿尔茨海默病（AD）中人类中枢神经系统的微小RNA（miRNA）信号传导——新的独特病理特征
Int J Mol Sci. 2015 Dec 17;16(12):30105-16. doi: 10.3390/ijms161226223.
10
MicroRNA target prediction in glaucoma.青光眼的微小RNA靶点预测
Prog Brain Res. 2015;220:217-40. doi: 10.1016/bs.pbr.2015.04.013. Epub 2015 Jun 30.

引用本文的文献

1
MicroRNA (miRNA) Complexity in Alzheimer's Disease (AD).阿尔茨海默病（AD）中的微小RNA（miRNA）复杂性
Biology (Basel). 2023 May 30;12(6):788. doi: 10.3390/biology12060788.
2
Endogenous miRNA-Based Innate-Immunity against SARS-CoV-2 Invasion of the Brain.内源性 miRNA 介导的固有免疫抵抗 SARS-CoV-2 对大脑的侵袭。
Int J Mol Sci. 2023 Feb 8;24(4):3363. doi: 10.3390/ijms24043363.
3
Understanding the Pivotal Role of the Vagus Nerve in Health from Pandemics.从大流行中理解迷走神经在健康中的关键作用。
Bioengineering (Basel). 2022 Jul 29;9(8):352. doi: 10.3390/bioengineering9080352.
4
Downregulation of Neurofilament Light Chain Expression in Human Neuronal-Glial Cell Co-Cultures by a Microbiome-Derived Lipopolysaccharide-Induced miRNA-30b-5p.微生物群衍生的脂多糖诱导的miRNA-30b-5p对人神经元-神经胶质细胞共培养物中神经丝轻链表达的下调作用
Front Neurol. 2022 Jun 24;13:900048. doi: 10.3389/fneur.2022.900048. eCollection 2022.

本文引用的文献

1
Circular RNA ITCH: An Emerging Multifunctional Regulator.环状 RNA ITCH：一种新兴的多功能调节因子。
Biomolecules. 2022 Feb 24;12(3):359. doi: 10.3390/biom12030359.
2
Systematic Review: microRNAs as Potential Biomarkers in Mild Cognitive Impairment Diagnosis.系统评价：微小RNA作为轻度认知障碍诊断中的潜在生物标志物
Front Aging Neurosci. 2022 Jan 12;13:807764. doi: 10.3389/fnagi.2021.807764. eCollection 2021.
3
Recent Developments in Positron Emission Tomography Tracers for Proteinopathies Imaging in Dementia.用于痴呆症中蛋白质病成像的正电子发射断层扫描示踪剂的最新进展
Front Aging Neurosci. 2022 Jan 3;13:751897. doi: 10.3389/fnagi.2021.751897. eCollection 2021.
4
Extracellular vesicles (exosomes and ectosomes) play key roles in the pathology of brain diseases.细胞外囊泡（外泌体和微囊泡）在脑部疾病的病理学中发挥关键作用。
Mol Biomed. 2021 Jun 20;2(1):18. doi: 10.1186/s43556-021-00040-5.
5
Small Molecule Drugs Targeting Non-Coding RNAs as Treatments for Alzheimer's Disease and Related Dementias.小分子药物靶向非编码 RNA 治疗阿尔茨海默病及相关痴呆。
Genes (Basel). 2021 Dec 17;12(12):2005. doi: 10.3390/genes12122005.
6
Co-Expression Network Analysis of Micro-RNAs and Proteins in the Alzheimer's Brain: A Systematic Review of Studies in the Last 10 Years.阿尔茨海默病大脑中 microRNAs 和蛋白质的共表达网络分析：对过去 10 年研究的系统综述。
Cells. 2021 Dec 9;10(12):3479. doi: 10.3390/cells10123479.
7
Inflamma-MicroRNAs in Alzheimer's Disease: From Disease Pathogenesis to Therapeutic Potentials.阿尔茨海默病中的炎症性微小RNA：从疾病发病机制到治疗潜力
Front Cell Neurosci. 2021 Oct 28;15:785433. doi: 10.3389/fncel.2021.785433. eCollection 2021.
8
Antisense oligonucleotides for Alzheimer's disease therapy: from the mRNA to miRNA paradigm.用于阿尔茨海默病治疗的反义寡核苷酸：从 mRNA 到 miRNA 范式。
EBioMedicine. 2021 Dec;74:103691. doi: 10.1016/j.ebiom.2021.103691. Epub 2021 Nov 10.
9
The promise of microRNA-based therapies in Alzheimer's disease: challenges and perspectives.基于 microRNA 的疗法在阿尔茨海默病中的应用前景：挑战与展望。
Mol Neurodegener. 2021 Nov 6;16(1):76. doi: 10.1186/s13024-021-00496-7.
10
Broad spectrum antiviral nucleosides-Our best hope for the future.广谱抗病毒核苷——我们对未来的最大希望。
Annu Rep Med Chem. 2021;57:109-132. doi: 10.1016/bs.armc.2021.09.001. Epub 2021 Oct 29.

Fission Impossible: Stabilized miRNA-Based Analogs in Neurodegenerative Disease.

作者信息

Lukiw Walter J

机构信息

LSU Neuroscience Center, Louisiana State University Health Science Center, New Orleans, LA, United States.

Department of Ophthalmology, Louisiana State University Health Science Center, New Orleans, LA, United States.

出版信息

Front Neurosci. 2022 May 3;16:875957. doi: 10.3389/fnins.2022.875957. eCollection 2022.

DOI:10.3389/fnins.2022.875957
PMID:35592255
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9111010/
Abstract
摘要