Center for Radiation Protection Knowledge, Oak Ridge National Laboratory, Oak Ridge, TN.
Medical Radiation Physics Malmö, ITM, Lund University, SE-205 02 Malmö, Sweden.
Health Phys. 2022 Aug 1;123(2):165-172. doi: 10.1097/HP.0000000000001571. Epub 2022 May 20.
Radiation dosimetry is central to virtually all radiation safety applications, optimization, and research. It relates to various individuals and population groups and to miscellaneous exposure situations-including planned, existing, and emergency situations. The International Commission on Radiological Protection (ICRP) has developed a new computational framework for internal dose estimations. Important components are more detailed and improved anatomical models and more realistic biokinetic models than before. The ICRP is currently producing new organ dose and effective dose coefficients for occupational intakes of radionuclides (OIR) and environmental intakes of radionuclides (EIR), which supersede the earlier dose coefficients in Publication 68 and the Publication 72 series, respectively. However, the ICRP only publishes dose coefficients for a single acute intake of a radionuclide and for an integration period of 50 years for intake by adults and to age 70 years for intakes by pre-adults. The new software, IDAC-Bio, performs committed absorbed dose and effective dose calculations for a selectable intake scenario, e.g., for a continuous intake or an intake during x hours per day and y days per week, and for any selected integration time. The software uses the primary data and models of the ICRP biokinetic models and numerically solves the biokinetic model and calculates the absorbed doses to organs and tissues in the ICRP reference human phantoms. The software calculates absorbed dose using the nuclear decay data in ICRP publication 107. IDAC-Bio is a further development and an important addition to the internal dosimetry program IDAC-Dose2.1. The results generated by the software were validated against published ICRP dose coefficients. The potential of the software is illustrated by dose calculations for a nuclear power plant worker who had been exposed to varying levels of 60 Co and who had undergone repeated whole-body measurements, and for a hypothetical member of the public subject to future releases of 148 Gd from neutron spallation in tungsten at the European Spallation Source.
辐射剂量学几乎是所有辐射安全应用、优化和研究的核心。它涉及到各种个体和人群群体以及各种暴露情况,包括计划中的、现有的和紧急情况。国际辐射防护委员会(ICRP)已经开发了一种新的内部剂量估算计算框架。重要组成部分是比以前更详细和改进的解剖模型和更现实的生物动力学模型。ICRP 目前正在为职业摄入放射性核素(OIR)和环境摄入放射性核素(EIR)产生新的器官剂量和有效剂量系数,分别取代早期出版物 68 和出版物 72 系列中的剂量系数。然而,ICRP 仅发布单次急性摄入放射性核素的剂量系数,以及成年人摄入 50 年和未成年人摄入至 70 岁的 50 年积分期的剂量系数。新的软件 IDAC-Bio 为可选择的摄入情况执行承诺吸收剂量和有效剂量计算,例如,对于连续摄入或每天 x 小时和每周 y 天摄入,以及任何选定的积分时间。该软件使用 ICRP 生物动力学模型的主要数据和模型,并数值求解生物动力学模型,计算 ICRP 参考人体模型中器官和组织的吸收剂量。该软件使用 ICRP 出版物 107 中的核衰变数据计算吸收剂量。IDAC-Bio 是内部剂量学程序 IDAC-Dose2.1 的进一步发展和重要补充。该软件生成的结果与已发布的 ICRP 剂量系数进行了验证。通过对暴露于不同水平 60 Co 的核电站工人和接受过重复全身测量的假想公众成员进行剂量计算,以及对欧洲散裂源钨中中子散裂产生的 148 Gd 未来释放进行剂量计算,说明了该软件的潜力。