Paquet F, Harrison J
a IRSN, PSE ENV SRTE, BP3, 13115 Saint Paul lez Durance, Cedex, France.
b Public Health England and Oxford Brookes University, UK.
Ann ICRP. 2018 Oct;47(3-4):63-74. doi: 10.1177/0146645318759620. Epub 2018 Apr 16.
Internal doses are calculated using biokinetic and dosimetric models. These models describe the behaviour of the radionuclides after ingestion, inhalation, and absorption to the blood, and the absorption of the energy resulting from their nuclear transformations. The International Commission on Radiological Protection (ICRP) develops such models and applies them to provide dose coefficients and bioassay functions for the calculation of equivalent or effective dose from knowledge of intakes and/or measurements of activity in bioassay samples. Over the past few years, ICRP has devoted a considerable amount of effort to the revision and improvement of models to make them more physiologically realistic representations of uptake and retention in organs and tissues, and of excretion. Provision of new biokinetic models, dose coefficients, monitoring methods, and bioassay data is the responsibility of Committee 2 and its task groups. Three publications in a series of documents replacing the ICRP Publication 30 series and ICRP Publications 54, 68, and 78 have been issued [Occupational Intakes of Radionuclides (OIR) Parts 1-3]. OIR Part 1 describes the assessment of internal occupational exposure to radionuclides, biokinetic and dosimetric models, methods of individual and workplace monitoring, and general aspects of retrospective dose assessment. OIR Parts 2-5 provide data on individual elements and their radioisotopes. Work is also in progress on revision of dose coefficients for radionuclide intakes by members of the public.
内照射剂量是使用生物动力学和剂量学模型来计算的。这些模型描述了放射性核素在摄入、吸入并吸收进入血液后以及其核转变产生的能量吸收后的行为。国际放射防护委员会(ICRP)开发此类模型并应用它们来提供剂量系数和生物测定函数,以便根据生物测定样本中的摄入量和/或活度测量值来计算当量剂量或有效剂量。在过去几年中,ICRP投入了大量精力对模型进行修订和改进,以使它们在器官和组织中的摄取、滞留以及排泄方面更符合生理实际情况。提供新的生物动力学模型、剂量系数、监测方法和生物测定数据是第2委员会及其任务组的职责。已发布了一系列取代ICRP第30号出版物系列以及ICRP第54、68和78号出版物的三份文件[放射性核素的职业摄入量(OIR)第1 - 3部分]。OIR第1部分描述了对放射性核素的内照射职业暴露评估、生物动力学和剂量学模型、个人和工作场所监测方法以及回顾性剂量评估的一般方面。OIR第2 - 5部分提供了关于单个元素及其放射性同位素的数据。针对公众成员摄入放射性核素的剂量系数修订工作也在进行中。