Department of Chinese Medicine, Chang Gung Memorial Hospital at Kaohsiung, Kaohsiung, Taiwan; Fooyin University College of Nursing, Kaohsiung, Taiwan; Kaohsiung Medical University College of Medicine, Kaohsiung, Taiwan; College of Medicine, Chang Gung University, Taoyuan, Taiwan.
Department of Psychiatry, Chang Gung Memorial Hospital at Kaohsiung, Kaohsiung, Taiwan; College of Medicine, Chang Gung University, Taoyuan, Taiwan.
Biomed J. 2022 Apr;45(2):414-423. doi: 10.1016/j.bj.2021.04.010. Epub 2021 May 1.
The incidence of opioid use disorder (OUD) is increasing worldwide, and the opioid-related overdose crisis is currently a major global challenge. This study investigated the effects of adjuvant laser meridian massage (LMM) in men with OUD undergoing methadone maintenance treatment (MMT).
A case-controlled study was conducted from February 2019 to April 2020. Fourteen men with OUD on MMT were enrolled from an addiction treatment center as an experimental group. An age-matched control group comprising 13 men was also enrolled. The experimental group received LMM on the back, including over the Bladder meridian and Governor Vessel, three times weekly for 4 weeks. The control group received only MMT. Urinary morphine levels, patients' self-reports of the number of episodes or days of heroin use, and visual analog scale scores for heroin craving/refusal to use heroin during the previous week were evaluated. Quality of life was reported using the Short Form (SF)-12v2.
The experimental group showed a significant decrease in heroin use (p < 0.05), whereas the control group showed a significant increase in heroin craving (p < 0.05). The SF-12v2 Health Survey revealed a significant improvement in physical health in the experimental group (P < 0.05).
The results of this study suggest that laser meridian massage can be considered a safe, well-tolerated, and potentially useful adjuvant intervention for opioid use disorder.
阿片类药物使用障碍（OUD）的发病率在全球范围内呈上升趋势，阿片类药物相关的过量危机目前是一个主要的全球挑战。本研究调查了辅助性激光经络按摩（LMM）对接受美沙酮维持治疗（MMT）的男性 OUD 患者的影响。
这是一项病例对照研究，于 2019 年 2 月至 2020 年 4 月进行。14 名接受 MMT 的男性 OUD 患者从一个成瘾治疗中心被纳入实验组。同时纳入了年龄匹配的 13 名男性对照组。实验组接受背部 LMM，包括膀胱经和任脉，每周 3 次，共 4 周。对照组仅接受 MMT。评估尿吗啡水平、患者自我报告的海洛因使用次数或天数，以及前一周海洛因渴求/拒绝使用海洛因的视觉模拟评分。使用短式健康调查问卷（SF-12v2）报告生活质量。
实验组的海洛因使用量显著减少（p<0.05），而对照组的海洛因渴求显著增加（p<0.05）。SF-12v2 健康调查显示实验组的身体健康状况显著改善（P<0.05）。
本研究结果表明，激光经络按摩可以被认为是一种安全、耐受良好、对阿片类药物使用障碍可能有用的辅助干预措施。
