Grandeo Jason, Favaro Laura, Rhon Daniel I, Young Jodi L
Bellin College, Green Bay, WI, USA.
University of Lynchburg, School of Physical Therapy, Lynchburg, VA, USA.
Musculoskeletal Care. 2022 Dec;20(4):796-811. doi: 10.1002/msc.1644. Epub 2022 May 20.
The aim of this systematic review was to assess the reproducibility of exercise therapy used in clinical trials for chronic neck pain (CNP) based on reported items from the Template for Intervention Description and Replication (TIDieR) and the Consensus on Exercise Reporting Template (CERT) checklists.
Two researchers systematically searched, screened, and selected trials that assessed exercise therapy for CNP between 2000 and 2021 from PubMed, CINAHL, and Ovid Medline. Included studies were published in English, and study participants experienced neck pain for longer than 3 months. Thoroughness of reporting of exercise therapy was assessed using the TIDierR and CERT checklists. Methodological quality of each study was screened with the Revised Cochrane Risk of Bias Tool. Data analysis was performed for descriptive and correlational statistics.
Sixty-three clinical trials using exercise therapy for treatment of CNP met the inclusion criteria. No study reported all TIDieR or CERT items. The mean number of items reported was 5.44 (SD 2.40, range of 1-11) on the TIDieR, and 8.27 (SD 4.14, range of 0-17) for the CERT. Risk of bias was high for 30 studies (47.6%), somewhat concerning for 20 studies (31.7%), and low for 13 studies (21.7%). Higher risk of bias was associated with a lower number of TIDieR and CERT items reported.
DISCUSSION & CONCLUSION: The majority of exercise therapy trials for CNP lack proper reporting, limiting reproducibility of the interventions in real world clinical practice and follow-on research. After checklists were published, reporting did not improve.
本系统评价旨在根据干预描述与复制模板（TIDieR）和运动报告模板共识（CERT）清单中报告的项目，评估用于慢性颈痛（CNP）临床试验的运动疗法的可重复性。
两名研究人员从PubMed、CINAHL和Ovid Medline系统检索、筛选并选择了2000年至2021年间评估CNP运动疗法的试验。纳入研究以英文发表，研究参与者颈痛持续时间超过3个月。使用TIDierR和CERT清单评估运动疗法报告的完整性。使用修订的Cochrane偏倚风险工具筛选每项研究的方法学质量。进行描述性和相关性统计分析。
63项使用运动疗法治疗CNP的临床试验符合纳入标准。没有研究报告所有TIDieR或CERT项目。TIDieR上报告项目的平均数量为5.44（标准差2.40，范围1 - 11），CERT为8.27（标准差4.14，范围0 - 17）。30项研究（47.6%）的偏倚风险高，20项研究（31.7%）的偏倚风险有些令人担忧，13项研究（21.7%）的偏倚风险低。较高的偏倚风险与报告的TIDieR和CERT项目数量较少有关。
大多数针对CNP的运动疗法试验报告不充分，限制了干预措施在现实世界临床实践和后续研究中的可重复性。清单发布后，报告情况并未改善。
