Institut für Diabetes-Technologie, Forschungs- und Entwicklungsgesellschaft mbH an der Universität Ulm, Ulm, Germany.
AMF Medical SA, Ecublens, Switzerland.
J Diabetes Sci Technol. 2023 Nov;17(6):1644-1648. doi: 10.1177/19322968221097997. Epub 2022 May 20.
A prototype of an insulin patch pump that operates with a double pump mechanism was tested. Accuracy of bolus delivery of 0.2 U and 1.0 U, and a basal rate of 1.0 U/h were evaluated with a microgravimetric method. In addition, occlusion detection time at basal rates of 0.1 U/h and 1.0 U/h was assessed. Mean deviation from target was lower than 2% for both bolus sizes. Regarding basal rate accuracy, mean deviation over 72 hours was lower than 1%. Occlusion detection occurred in less than 30 minutes with both basal rates. Our study results suggest that the tested pump prototype provides delivery accuracy and occlusion detection that is similar or even better compared to all commercially available pumps tested with a similar experimental approach.
我们对一种采用双泵机制运行的胰岛素贴片泵原型进行了测试。采用微量天平法对 0.2U 和 1.0U 的推注剂量准确性以及 1.0U/h 的基础输注率进行了评估。此外，还评估了在 0.1U/h 和 1.0U/h 的基础输注率下的阻塞检测时间。对于两种推注剂量，实际值与目标值的平均偏差均低于 2%。关于基础输注率的准确性，72 小时内的平均偏差低于 1%。两种基础输注率下，阻塞检测均在 30 分钟内完成。我们的研究结果表明，与使用类似实验方法测试的所有市售泵相比，所测试的泵原型在输注准确性和阻塞检测方面具有相似甚至更好的性能。
