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描述一种新型胰岛素给药贴片泵及其比较准确性评估。

Description of a Novel Patch Pump for Insulin Delivery and Comparative Accuracy Evaluation.

机构信息

Institut für Diabetes-Technologie, Forschungs- und Entwicklungsgesellschaft mbH an der Universität Ulm, Ulm, Germany.

Terumo Corporation, Tokyo, Japan.

出版信息

J Diabetes Sci Technol. 2022 Jul;16(4):971-975. doi: 10.1177/19322968211000441. Epub 2021 Mar 19.

DOI:10.1177/19322968211000441
PMID:33736474
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9264447/
Abstract

A new insulin patch pump for continuous subcutaneous insulin infusion was developed. The pump is composed of reusable and disposable parts and operates with a stepping motor. This pump was compared to a patch pump and a durable pump regarding basal rate and bolus accuracy. Using a microgravimetric method, boluses of 0.2 U, 1 U and 7 U, and a basal rate of 1 U/h were tested. For all pumps, bolus accuracy was higher when larger volumes were delivered. While median deviations were similar for all pumps, there were differences in the precision of individual boluses and when regarding basal rate delivery divided into 1-h windows.

摘要

研发出一种新的胰岛素贴片泵,用于持续皮下胰岛素输注。该泵由可重复使用和一次性部件组成,采用步进电机运行。该泵在基础率和推注精度方面与贴片泵和耐用泵进行了比较。使用微量天平法,对 0.2U、1U 和 7U 的推注量以及 1U/h 的基础率进行了测试。对于所有的泵,当输送的体积较大时,推注精度更高。虽然所有泵的中位数偏差相似,但个别推注的精度以及将基础率输送分为 1 小时窗口时存在差异。

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本文引用的文献

1
Accuracy assessment of bolus and basal rate delivery of different insulin pump systems used in insulin pump therapy of children and adolescents.评估不同胰岛素泵系统在儿童和青少年胰岛素泵治疗中输注剂量的准确性。
Pediatr Diabetes. 2020 Jun;21(4):649-656. doi: 10.1111/pedi.12993. Epub 2020 Feb 7.
2
Accuracy of Bolus and Basal Rate Delivery of Different Insulin Pump Systems.不同胰岛素输注系统输注剂量的准确性。
Diabetes Technol Ther. 2019 Apr;21(4):201-208. doi: 10.1089/dia.2018.0376. Epub 2019 Mar 22.
3
Establishing Methods to Determine Clinically Relevant Bolus and Basal Rate Delivery Accuracy of Insulin Pumps.
建立确定胰岛素泵临床相关大剂量和基础输注率准确性的方法。
J Diabetes Sci Technol. 2019 Jan;13(1):60-67. doi: 10.1177/1932296818788349. Epub 2018 Jul 13.
4
Continuous subcutaneous insulin infusion in diabetes: patient populations, safety, efficacy, and pharmacoeconomics.糖尿病患者皮下胰岛素持续输注:患者群体、安全性、有效性及药物经济学
Diabetes Metab Res Rev. 2016 Jan;32(1):21-39. doi: 10.1002/dmrr.2653. Epub 2015 Jun 22.