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一名癫痫患者感染 COVID-19 后发生的感染后小脑性共济失调。

Post-infectious cerebellar ataxia following COVID-19 in a patient with epilepsy.

作者信息

Chattopadhyay Sidhartha, Sengupta Judhajit, Basu Sagar

机构信息

Department of Critical Care Medicine R.N Tagore International Institute of Cardiac Sciences, Mukundapur Kolkata India.

Department of Neuro-medicine KPC Medical College & Hospital, Jadavpur Kolkata India.

出版信息

Clin Exp Neuroimmunol. 2022 May 2. doi: 10.1111/cen3.12700.

Abstract

BACKGROUND

Various neurological manifestations have been described in relation to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and coronavirus disease 2019 (COVID-19). However, the development of cerebellar ataxia after recovery from COVID-19 is rare. We present a case of cerebellar ataxia 3 weeks after recovery from COVID-19.

CASE PRESENTATION

A 70-year-old male patient from an urban area of India presented with ataxia. He was hypertensive and had been receiving treatment for post-traumatic epilepsy for the previous 3 years. He had previously had laboratory-confirmed COVID-19 infection with mild symptoms that resolved within 2 weeks. However, 3 weeks after symptom improvement, he developed severe pan-cerebellar ataxia. Investigations were suggestive of post-infectious cerebellar ataxia. Other causes of ataxia were excluded. He responded well to pulse methylprednisolone therapy and was discharged with mild tremor and ataxia.

CONCLUSION

Post-infectious cerebellar ataxia is an unusual presentation after COVID-19. The clinician should be aware of such complications following COVID-19 infection as early diagnosis and proper management leads to better outcomes in many patients.

摘要

背景

与严重急性呼吸综合征冠状病毒2(SARS-CoV-2)感染和2019冠状病毒病(COVID-19)相关的各种神经学表现已被描述。然而,COVID-19康复后出现小脑共济失调的情况很少见。我们报告一例COVID-19康复3周后出现小脑共济失调的病例。

病例介绍

一名来自印度市区的70岁男性患者出现共济失调。他患有高血压,在过去3年中一直在接受创伤后癫痫的治疗。他之前经实验室确诊感染COVID-19,症状较轻,在2周内缓解。然而,症状改善3周后,他出现了严重的全小脑共济失调。检查提示为感染后小脑共济失调。排除了其他导致共济失调的原因。他对脉冲甲基强的松龙治疗反应良好,出院时仍有轻度震颤和共济失调。

结论

感染后小脑共济失调是COVID-19后的一种不寻常表现。临床医生应意识到COVID-19感染后的此类并发症,因为早期诊断和适当管理可使许多患者获得更好的预后。

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Myoclonus-Ataxia Syndrome Associated with COVID-19.与新型冠状病毒肺炎相关的肌阵挛-共济失调综合征
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