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[双对比结肠造影。4种结肠准备方法的比较性随机研究]

[Double-contrast colonic radiography. Comparative, randomized study of 4 colon preparations].

作者信息

Sebag G, Bellin M F, Cohen S, Grellet J

出版信息

J Radiol. 1987 Jan;68(1):31-4.

PMID:3560028
Abstract

Since diagnostic value of double contrast colon imaging is dependent on the colon preparation used, tolerance and efficacy of 4 colon preparations were evaluated by a simple-blind, comparative, randomized study in 185 outpatients. Colon preparation involves variable combinations of 3 means: residue-free diet, laxatives and wash-out enemas. Principal criteria were evaluated under blind conditions by the same investigator during all examinations, with quantitative rating by segment (left, transverse and right colon) of adherence and colon cleanliness, and global assessment of quality of preparation. The 4 groups were comparable: mean age 44.7 years, sex ratio (male/female) 51.3%. Tolerance and compliance were elevated without significant inter-group differences. The colon preparations studied did not allow a homogeneous preparation to be obtained throughout the colon, efficacy in left colon being superior to right colon, whatever the method used. Analysis of cleanliness and adherence by segment failed to show significant differences between procedures, probably related to weak differences in their effectiveness and the strict nature of the study. The use of a global criterion tended to show value of wash-out enemas as a routine procedure, whether in outpatients or in the Radiology department.

摘要

由于双重对比结肠成像的诊断价值取决于所采用的结肠准备情况,因此通过一项简单盲法、比较性、随机研究,对185例门诊患者使用的4种结肠准备方法的耐受性和有效性进行了评估。结肠准备包括三种方法的不同组合:无残渣饮食、泻药和灌肠冲洗。在所有检查过程中,由同一名检查者在盲法条件下评估主要标准,通过对结肠各段(左半结肠、横结肠和右半结肠)的附着情况和结肠清洁度进行定量评分,并对准备质量进行整体评估。这4组具有可比性:平均年龄44.7岁,性别比(男/女)为51.3%。耐受性和依从性有所提高,但组间无显著差异。所研究的结肠准备方法无法使整个结肠获得均匀的准备效果,无论采用何种方法,左半结肠的效果均优于右半结肠。按段分析清洁度和附着情况未能显示出不同方法之间存在显著差异,这可能与它们有效性的差异较小以及研究的严格性有关。采用整体标准倾向于表明,灌肠冲洗作为一种常规方法具有价值,无论是在门诊患者还是在放射科。

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