Lee J R, Ferrando J R
Gut. 1984 Jan;25(1):69-72. doi: 10.1136/gut.25.1.69.
This study examines which methods are most appropriate for preparation of the large bowel for double contrast barium enema. Two proprietary laxatives, X-Prep and Picolax, mechanical colonic lavage, and dietary restriction were evaluated in a randomised study of 160 patients. Four alternative preparations were compared with or without dietary restriction. The four preparations were X-Prep alone, X-Prep plus lavage, Picolax alone, and Picolax plus lavage. Scoring of the radiographs was carried out on a double blind basis. Picolax proved superior to X-Prep overall (p less than 0.01) but this was almost entirely because of its greater effect in the right colon and transverse colon. Cleansing in the left colon and rectosigmoid was similar with both laxatives. Restriction of solid food improved bowel cleansing and gave better results than mechanical lavage. The addition of a colonic lavage in starved patients did not significantly improve the quality of bowel preparation with either laxative.
本研究探讨了哪种方法最适合用于双重对比钡灌肠检查时的大肠准备。在一项对160例患者的随机研究中，对两种专利缓泻剂X-Prep和比沙可啶、机械性结肠灌洗以及饮食限制进行了评估。比较了四种不同的准备方法，包括有无饮食限制的情况。这四种准备方法分别是单独使用X-Prep、X-Prep加灌洗、单独使用比沙可啶以及比沙可啶加灌洗。X线片的评分采用双盲方式进行。总体而言，比沙可啶被证明优于X-Prep（p<0.01），但这几乎完全是因为它在右半结肠和横结肠的效果更佳。两种缓泻剂在左半结肠和直肠乙状结肠的清洁效果相似。限制固体食物可改善肠道清洁，且比机械性灌洗效果更好。在饥饿患者中添加结肠灌洗，两种缓泻剂的肠道准备质量均未得到显著改善。
