Gabriel S E, Conn D L, Phyliky R L, Pittelkow M R, Scott R E
J Rheumatol. 1986 Dec;13(6):1167-72.
Systemic vasculitis is an unusual but recently recognized complication of hairy cell leukemia. We studied this relationship further in an attempt to better understand pathogenetic mechanisms of vasculitis. We examined the records of 129 cases of hairy cell leukemia seen at the Mayo Clinic between 1976 and 1983, and identified 2 cases with evidence of systemic vasculitis. The first of these cases is discussed in detail. Immunologic studies were performed but we were unable to demonstrate the presence of shared antigen on hairy cells and endothelial cells. The literature is reviewed and reports of this association are summarized. Possible mechanisms of vascular injury are discussed.
系统性血管炎是毛细胞白血病一种罕见但近来已被认识到的并发症。我们进一步研究了这种关系，试图更好地理解血管炎的发病机制。我们查阅了1976年至1983年间在梅奥诊所就诊的129例毛细胞白血病患者的病历，确定了2例有系统性血管炎证据的病例。其中第一例病例将详细讨论。我们进行了免疫学研究，但未能证实在毛细胞和内皮细胞上存在共同抗原。本文对相关文献进行了综述，并总结了有关这种关联的报道。还讨论了血管损伤的可能机制。
