Krasin Elisha, Warschawski Yaniv, Morgan Samuel, Dekel Michal
Division of Orthopedic Surgery, Tel Aviv Sourasky Medical Center, Affiliated with the Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Maccabi Healthcare Services, Tel Aviv, Israel.
J Orthop. 2022 May 13;32:68-71. doi: 10.1016/j.jor.2022.05.008. eCollection 2022 Jul-Aug.
The current practice of antibiotic prophylaxis in orthopedic surgery has existed almost 50 years yet little changes have been made. The incidence of methicillin resistant and multi-drug resistant Gram-negative bacteria is growing.
We studied the positive cultures after primary hip and knee joint replacement and trauma surgery at our department.
Our investigation substantiates the current reports of an increase in oxacillin resistance of and an increase in incidence of Gram-negative bacteria. The standard use of cephalosporins for prophylaxis does not provide the necessary protection that it used to. We suggest that the recommendations and practice of antibiotic prophylaxis should be reconsidered.
Level III - retrospective cohort study.
骨科手术中抗生素预防的现行做法已存在近50年，但几乎没有什么变化。耐甲氧西林和多重耐药革兰氏阴性菌的发生率正在上升。
我们研究了本部门初次髋关节和膝关节置换术及创伤手术后的阳性培养结果。
我们的调查证实了目前关于苯唑西林耐药性增加和革兰氏阴性菌发生率增加的报道。标准使用头孢菌素进行预防并不能提供过去那样的必要保护。我们建议重新考虑抗生素预防的建议和做法。
三级——回顾性队列研究。
