Brillantino Carmela, Errico Maria Elena, Minelli Rocco, Gaglione Giovanni, Pirisi Pietro, Rossi Antonio, Menna Biagio Francesco, Santarsiere Marika, Rumolo Mariateresa, Rossi Eugenio
Department of Radiology - "AORN Santobono Pausilipon", Pediatric Hospital, Naples, Italy.
Department of Pathology - "AORN Santobono Pausilipon", Pediatric Hospital, Naples, Italy.
Radiol Case Rep. 2022 May 7;17(7):2416-2423. doi: 10.1016/j.radcr.2022.03.107. eCollection 2022 Jul.
Malignant germ cell tumors constitute about 3%-4% of all neoplasms occurring before the age of 15. They arise in the ovaries, the testes, and in several other locations, including the lower back, the chest, the brain, and the abdomen. In infants and young children, the sacrococcygeal region is the most common site for extragonadal germ cell tumors, and teratomas account for the vast majority of sacrococcygeal germ cell tumors. Neonatal sacrococcygeal teratomas are usually benign and rarely they may contain a malignant component that is predominantly a yolk sac tumor. In this article, we describe a rare case of a male newborn with a giant sacrococcygeal mixed germ cell tumor composed of grade 3 immature teratoma and malignant yolk sac elements.
恶性生殖细胞肿瘤约占15岁前发生的所有肿瘤的3%-4%。它们起源于卵巢、睾丸以及其他几个部位，包括下背部、胸部、大脑和腹部。在婴幼儿中，骶尾部是性腺外生殖细胞肿瘤最常见的部位，畸胎瘤占骶尾部生殖细胞肿瘤的绝大多数。新生儿骶尾部畸胎瘤通常是良性的，很少含有主要为卵黄囊瘤的恶性成分。在本文中，我们描述了一例罕见的男性新生儿病例，其患有巨大的骶尾部混合性生殖细胞肿瘤，由3级未成熟畸胎瘤和恶性卵黄囊成分组成。
