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A novel PI3K inhibitor XH30 suppresses orthotopic glioblastoma and brain metastasis in mice models.一种新型PI3K抑制剂XH30可抑制小鼠模型中的原位胶质母细胞瘤和脑转移。
Acta Pharm Sin B. 2022 Feb;12(2):774-786. doi: 10.1016/j.apsb.2021.05.019. Epub 2021 May 26.
2
Navigating Calcium and Reactive Oxygen Species by Natural Flavones for the Treatment of Heart Failure.天然黄酮类化合物调控钙和活性氧以治疗心力衰竭
Front Pharmacol. 2021 Nov 9;12:718496. doi: 10.3389/fphar.2021.718496. eCollection 2021.
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Resistance to immunotherapy in human malignancies: Mechanisms, research progresses, challenges, and opportunities.人类恶性肿瘤对免疫疗法的抗性：机制、研究进展、挑战与机遇
J Cell Physiol. 2022 Jan;237(1):346-372. doi: 10.1002/jcp.30575. Epub 2021 Sep 8.
4
Multidrug resistance proteins (MRPs): Structure, function and the overcoming of cancer multidrug resistance.多药耐药蛋白（MRPs）：结构、功能与克服肿瘤多药耐药性。
Drug Resist Updat. 2021 Jan;54:100743. doi: 10.1016/j.drup.2021.100743. Epub 2021 Jan 13.
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Sapitinib Reverses Anticancer Drug Resistance in Colon Cancer Cells Overexpressing the ABCB1 Transporter.沙匹替尼逆转过表达ABCB1转运蛋白的结肠癌细胞中的抗癌药物耐药性。
Front Oncol. 2020 Oct 9;10:574861. doi: 10.3389/fonc.2020.574861. eCollection 2020.
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Mechanisms of Cancer Resistance to Immunotherapy.癌症对免疫疗法的耐药机制。
Front Oncol. 2020 Aug 6;10:1290. doi: 10.3389/fonc.2020.01290. eCollection 2020.
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Repurposing old drugs to fight multidrug resistant cancers.将老药重新用于治疗多药耐药性癌症。
Drug Resist Updat. 2020 Sep;52:100713. doi: 10.1016/j.drup.2020.100713. Epub 2020 Jun 25.
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An overview of drug discovery and development.药物发现与开发概述。
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Natural Products as Sources of New Drugs over the Nearly Four Decades from 01/1981 to 09/2019.天然产物：1981 年 1 月至 2019 年 9 月近四十年来的新药来源
J Nat Prod. 2020 Mar 27;83(3):770-803. doi: 10.1021/acs.jnatprod.9b01285. Epub 2020 Mar 12.
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Nat Commun. 2020 Jan 23;11(1):437. doi: 10.1038/s41467-019-14218-7.

Editorial: Novel Small-Molecule Agents in Overcoming Multidrug Resistance in Cancers.

作者信息

Cui Qingbin, Wang Cong, Zeng Leli, Zhou Qian-Xiong, Fan Ying-Fang

机构信息

Department of Cell and Cancer Biology, University of Toledo College of Medicine and Life Sciences, Toledo, OH, United States.

State Key Laboratory of Esophageal Cancer Prevention and Treatment, School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou, China.

出版信息

Front Chem. 2022 May 4;10:921985. doi: 10.3389/fchem.2022.921985. eCollection 2022.

DOI:10.3389/fchem.2022.921985
PMID:35601552
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9114663/
Abstract
摘要