Vasquez-Elera Luis E, Failoc-Rojas Virgilio E, Martinez-Rivera Raisa N, Morocho-Alburqueque Noelia, Temoche-Rivas Mario S, Valladares-Garrido Mario J
MD, Gastroenterology Service, Cayetano Heredia Hospital, 150 Independencia Avenue, Piura 200104, Peru.
MD, MSc(c), Research Unit for Generation and Synthesis Evidence in Health, Universidad San Ignacio de Loyola, 505 La Fontana Avenue, Lima 15012, Peru.
Germs. 2022 Mar 31;12(1):46-53. doi: 10.18683/germs.2022.1305. eCollection 2022 Mar.
This study aimed to identify factors associated with self-medication in patients with COVID-19.
A cross-sectional study was conducted using medical records of patients with COVID-19 who self-medicated before admission to a hospital in Piura, Peru. Prevalence ratios and 95% confidence intervals were estimated using generalized linear models with Poisson distribution family, log link function, and robust variance.
Out of 301 patients, 165 (54.8%) self-medicated before hospital admission, being more frequent self-medication with ivermectin (85.5%) and azithromycin (71.5%). The frequency of self-medication in those aged between 30-59 years was 2.53-fold higher than in those between 18-29 years. Male patients, dyslipidemia, smoking, and hepatic steatosis were associated with self-medication. Clinical characteristics associated with self-medication were fever, cough, headache, anosmia, dysgeusia, nausea/vomiting, and gastroesophageal reflux.
A high frequency of self-medication before hospital admission was observed in Peruvian patients with COVID-19, mainly of drugs without proven efficacy.
本研究旨在确定与新冠病毒疾病（COVID-19）患者自我药疗相关的因素。
采用横断面研究，利用秘鲁皮斯科一家医院收治的新冠病毒疾病（COVID-19）患者入院前自我药疗的病历。使用具有泊松分布族、对数链接函数和稳健方差的广义线性模型估计患病率比和95%置信区间。
在301例患者中，165例（54.8%）在入院前进行了自我药疗，其中使用伊维菌素（85.5%）和阿奇霉素（71.5%）进行自我药疗更为频繁。30至59岁人群的自我药疗频率比18至29岁人群高2.53倍。男性患者、血脂异常、吸烟和肝脂肪变性与自我药疗有关。与自我药疗相关的临床特征为发热、咳嗽、头痛、嗅觉丧失、味觉障碍、恶心/呕吐和胃食管反流。
在秘鲁的新冠病毒疾病（COVID-19）患者中，观察到入院前自我药疗的频率较高，主要是使用未经证实疗效的药物。
