de Figueiredo Alexandre, Larson Heidi J
Department of Infectious Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, UK.
Department of Health Metrics Sciences, University of Washington, Seattle, WA USA.
Commun Med (Lond). 2021 Sep 9;1:30. doi: 10.1038/s43856-021-00027-x. eCollection 2021.
As the world begins the rollout of multiple COVID-19 vaccines, pandemic exit strategies hinge on widespread acceptance of these vaccines. In this study, we perform a large-scale global exploratory study to examine the levels of COVID-19 vaccine acceptance and explore sociodemographic determinants of acceptance.
Between October 31, 2020 and December 15, 2020, 26,759 individuals were surveyed across 32 countries via nationally representative survey designs. Bayesian methods are used to estimate COVID-19 vaccination acceptance and explore the sociodemographic determinants of uptake, as well as the link between self-reported health and faith in the government's handling of the pandemic and acceptance.
Here we show that intent to accept a COVID-19 vaccine is low in Lebanon, France, Croatia, and Serbia and there is population-level polarisation in acceptance in Poland and Pakistan. Averaged across all countries, being male, over 65, having a high level of education, and believing that the government is handling the pandemic well are associated with increased stated acceptance, but there are country-specific deviations. A belief that the government is handling the pandemic well in Brazil and the United States is associated with lower vaccination intent. In the United Kingdom, we find that approval of the first COVID-19 vaccine in December 2020 did not appear to have an impact on the UK's vaccine acceptance, though as rollout has continued into 2021, the UK's uptake exceeds stated intent in large-scale surveys conducted before rollout.
Identifying factors that may modulate uptake of novel COVID-19 vaccines can inform effective immunisation programmes and policies. Differential stated intent to accept vaccines between socio-demographic groups may yield insights into the specific causes of low confidence and may suggest and inform targeted communication policies to boost confidence.
随着全球开始推广多种新冠疫苗，疫情退出策略取决于这些疫苗能否被广泛接受。在本研究中，我们开展了一项大规模的全球探索性研究，以调查新冠疫苗的接受程度，并探索接受疫苗的社会人口学决定因素。
在2020年10月31日至2020年12月15日期间，通过具有全国代表性的调查设计，对32个国家的26759人进行了调查。采用贝叶斯方法来估计新冠疫苗接种的接受程度，探索接种的社会人口学决定因素，以及自我报告的健康状况、对政府应对疫情措施的信心与疫苗接受程度之间的联系。
我们发现，黎巴嫩、法国、克罗地亚和塞尔维亚接受新冠疫苗的意愿较低，波兰和巴基斯坦在疫苗接受程度上存在群体层面的两极分化。在所有国家中，男性、65岁以上、受教育程度高以及认为政府应对疫情得力与更高的疫苗接受意愿相关，但也存在因国家而异的偏差。在巴西和美国，认为政府应对疫情得力与较低的疫苗接种意愿相关。在英国，我们发现2020年12月首款新冠疫苗获批似乎并未对英国的疫苗接受程度产生影响，不过随着疫苗接种工作持续到2021年，英国的接种率超过了在大规模疫苗接种前调查中所表明的意愿。
确定可能影响新型新冠疫苗接种的因素可为有效的免疫规划和政策提供参考。社会人口群体在疫苗接受意愿上的差异可能有助于深入了解信心不足的具体原因，并可能为增强信心的针对性宣传政策提供建议和参考。
