椎间盘-黄斑距离与脉络膜厚度：它们之间有关系吗？

Disc-fovea distance and choroidal thickness: is there a relationship?

作者信息

Cevher Selim, Barış Üçer Mehmet, Şahin Tayfun

机构信息

Assistant Professor of Ophthalmology, Department of Ophthalmology, Faculty of Medicine, Hitit University, 019040 Çorum, Turkey.

Department of Ophthalmology, Minister of Health Hitit University Erol Olçok Education and Research Hospital, Çorum, Turkey.

出版信息

Ther Adv Ophthalmol. 2022 May 15;14:25158414221096062. doi: 10.1177/25158414221096062. eCollection 2022 Jan-Dec.

DOI:10.1177/25158414221096062

PMID:35602660

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9121458/

Abstract

BACKGROUND

The distance between the optic disc center and the fovea is a biometric parameter; however, it is unclear whether DFD (disc-fovea distance) affects the choroidal thickness.

OBJECTIVE

The aim of this study is to investigate the association between DFD and choroidal thickness.

DESIGN

This is a prospective, and cross-sectional study.

METHODS

Two hundred fifty eyes of 250 healthy participants were examined in terms of DFD, age, axial length, spherical equivalent, and choroidal thickness. Inclusion criteria included aged between 20-40 years, no posterior segment disorders, and participants with best-corrected visual acuity (10/10 according to Snellen's chart). Participants with high hypermetropia (>4 diopter) or myopia (>6 diopter) or any systemic disease likely to affect choroidal thickness were excluded. Choroidal thickness measurements were performed at subfoveal, 1.0 mm temporal, and 1.0 mm nasal using the enhanced-depth imaging optical coherence tomography.

RESULTS

The mean age of all the participants was 26.21 ± 5.73 years, mean DFD was 4634.29 ± 274.70 µm, mean axial length was 23.62 ± 0.83 mm, and mean spherical equivalent was -0.61 ± 1.06 diopter. The mean subfoveal, nasal, and temporal choroidal thicknesses were 388.73 ± 90.15 µm, 351.26 ± 88.09 µm, and 366.50 ± 79.56 µm, respectively. A negative correlation was found between subfoveal, nasal, and temporal choroidal thicknesses and axial length ( = -0.157, = 0.013; = -0.168, = 0.008; = -0.174, = 0.006, respectively). Insignificant correlation was found between choroidal thicknesses and spherical equivalent ( > 0.05). There was not a statistically significant correlation between DFD and subfoveal, nasal, and temporal choroidal thicknesses ( = -0.028, = 0.655; = 0.030, = 0.641; = -0.025, = 0.699, respectively). In addition, there was not a statistically significant correlation between age and choroidal thickness.

CONCLUSION

This study shows that DFD and spherical equivalent do not affect choroidal thickness; axial length negatively affects choroidal thickness. In addition, age does not affect choroidal thickness between 20 and 40 years.

摘要

背景

视盘中心与黄斑中心凹之间的距离是一个生物特征参数；然而，视盘-黄斑中心凹距离（DFD）是否影响脉络膜厚度尚不清楚。

目的

本研究旨在探讨DFD与脉络膜厚度之间的关联。

设计

这是一项前瞻性横断面研究。

方法

对250名健康参与者的250只眼睛进行了DFD、年龄、眼轴长度、等效球镜度和脉络膜厚度的检查。纳入标准包括年龄在20至40岁之间、无后段疾病以及最佳矫正视力（根据斯内伦视力表为10/10）的参与者。排除高度远视（>4屈光度）或近视（>6屈光度）或任何可能影响脉络膜厚度的全身性疾病的参与者。使用增强深度成像光学相干断层扫描在黄斑中心凹下、颞侧1.0 mm和鼻侧1.0 mm处测量脉络膜厚度。

结果

所有参与者的平均年龄为26.21±5.73岁，平均DFD为4634.29±274.70 µm，平均眼轴长度为23.62±0.83 mm，平均等效球镜度为-0.61±1.06屈光度。黄斑中心凹下、鼻侧和颞侧脉络膜的平均厚度分别为388.73±90.15 µm、351.26±88.09 µm和366.50±79.56 µm。黄斑中心凹下、鼻侧和颞侧脉络膜厚度与眼轴长度之间均呈负相关（分别为r=-0.157，P=0.013；r=-0.168，P=0.008；r=-0.174，P=0.006）。脉络膜厚度与等效球镜度之间无显著相关性（P>0.05）。DFD与黄斑中心凹下、鼻侧和颞侧脉络膜厚度之间无统计学显著相关性（分别为r=-0.028，P=0.655；r=0.030，P=0.641；r=-0.025，P=0.699）。此外，年龄与脉络膜厚度之间无统计学显著相关性。