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应用扫频源光学相干断层扫描仪测量正常印度人眼的脉络膜厚度。

Choroidal thickness in normal Indian eyes using swept-source optical coherence tomography.

机构信息

Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India.

出版信息

Indian J Ophthalmol. 2019 Feb;67(2):252-255. doi: 10.4103/ijo.IJO_668_18.

Abstract

PURPOSE

The purpose of this study is to provide normative database for subfoveal choroidal thickness in Indian eyes using swept-source optical coherence tomography.

METHODS

This is a cross-sectional study based at a tertiary eye care center in Northern India. Two hundred and thirty eight eyes of 119 healthy subjects were examined in terms of axial length, spherical equivalent, and choroidal thickness. Inclusion criteria included age 19-60 years, no retinal or choroidal disorder, and patients with clear media and good fixation. Patients with high hypermetropia (>4 D) or myopia (>6 D) or any systemic disease likely to affect choroidal thickness were excluded. Twelve radial line scans were obtained centered on the fovea that were used to calculate choroidal and retinal thickness in 9 early treatment diabetic retinopathy study (ETDRS) zones.

RESULTS

The mean age of all the subjects was 28.70 ± 11.28 years; mean axial length was 23.63 ± 1.96 mm, and mean spherical equivalent was - 0.92 ± 3.08 D. The mean subfoveal choroidal thickness was 299.10 ± 131.2 μ and mean foveal thickness was 239.92 ± 48.16 μ. A negative correlation was found between subfoveal choroidal thickness and age (r = -0.0961, P = 0.1392) and axial length (r = -0.3166, P < 0.001). A statistically significant positive correlation was found between subfoveal choroidal thickness and refractive error (r = 0.2393, P = 0.0002).

CONCLUSION

This study provides normative database for subfoveal choroidal thickness and foveal thickness using swept-source optical coherence tomography. The choroidal thickness measured with swept-source platform is slightly higher than that reported with spectral domain platforms.

摘要

目的

本研究旨在利用扫频源光学相干断层扫描(OCT)为印度人眼的黄斑下脉络膜厚度提供参考数据库。

方法

这是一项在印度北部一家三级眼科中心进行的横断面研究。对 119 名健康受试者的 238 只眼进行了眼轴长度、等效球镜和脉络膜厚度检查。纳入标准包括年龄 19-60 岁、无视网膜或脉络膜疾病、以及有清晰的眼部和良好的固视能力的患者。排除高度远视(>4 D)或近视(>6 D)或任何可能影响脉络膜厚度的系统性疾病的患者。在黄斑中心进行了 12 条径向线扫描,以计算 9 个早期糖尿病性视网膜病变研究(ETDRS)区域的脉络膜和视网膜厚度。

结果

所有受试者的平均年龄为 28.70 ± 11.28 岁;平均眼轴长度为 23.63 ± 1.96mm,平均等效球镜为-0.92 ± 3.08D。黄斑下脉络膜平均厚度为 299.10 ± 131.2μm,黄斑中心凹平均厚度为 239.92 ± 48.16μm。研究发现,黄斑下脉络膜厚度与年龄(r=-0.0961,P=0.1392)和眼轴长度(r=-0.3166,P<0.001)呈负相关。同时还发现,黄斑下脉络膜厚度与屈光不正(r=0.2393,P=0.0002)呈显著正相关。

结论

本研究利用扫频源 OCT 为黄斑下脉络膜厚度和黄斑中心凹厚度提供了参考数据库。使用扫频源平台测量的脉络膜厚度略高于使用光谱域平台报告的结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a1b7/6376823/9d4540de97ac/IJO-67-252-g001.jpg

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