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肠易激综合征中的益生菌:其治疗作用综述

Probiotics in Irritable Bowel Syndrome: A Review of Their Therapeutic Role.

作者信息

Satish Kumar Lakshmi, Pugalenthi Lakshmi Sree, Ahmad Mahlika, Reddy Sanjana, Barkhane Zineb, Elmadi Jalal

机构信息

Internal Medicine, University of Perpetual Help System DALTA, Manila, PHL.

Internal Medicine, Bicol Christian College of Medicine, Legazpi City, PHL.

出版信息

Cureus. 2022 Apr 18;14(4):e24240. doi: 10.7759/cureus.24240. eCollection 2022 Apr.

DOI:10.7759/cureus.24240
PMID:35602835
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9116469/
Abstract

Irritable bowel syndrome (IBS) is a chronic collection of symptoms and lowers the quality of life. The management of such patients has always involved mitigating the symptoms produced by this disorder. This article reviews the role of probiotics in IBS by compiling various studies to deduce the possible symptomatic relief that probiotics may provide to IBS patients. Given the encouraging part of probiotics in abundant other gastrointestinal conditions, this article focuses on understanding the specific functional effects (if any) that are brought about by adding probiotics in patients with different types of IBS such as IBS with predominant constipation, IBS with predominant diarrhea, and even the unclassified type of IBS. The purpose of analyzing the role of probiotics is to study the changes brought about by them at the level of the gut microbiota in patients suffering from IBS, as this may prove to be of prime importance in managing such conditions with time. This article has also furnished an overview of the pathogenesis, diagnostic criteria, treatment modalities, sources of probiotics, and their therapeutic significance in IBS patients.

摘要

肠易激综合征(IBS)是一组慢性症状,会降低生活质量。这类患者的治疗一直包括减轻这种疾病产生的症状。本文通过汇总各种研究来推断益生菌可能为IBS患者提供的症状缓解,从而综述益生菌在IBS中的作用。鉴于益生菌在许多其他胃肠道疾病中发挥的积极作用,本文着重了解在不同类型的IBS患者(如以便秘为主的IBS、以腹泻为主的IBS以及未分类的IBS)中添加益生菌所带来的特定功能效应(若有)。分析益生菌作用的目的是研究它们在IBS患者肠道微生物群水平上所引起的变化,因为这可能对长期管理此类病症至关重要。本文还概述了IBS患者的发病机制、诊断标准、治疗方式、益生菌来源及其治疗意义。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fdf0/9116469/3795b21244c3/cureus-0014-00000024240-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fdf0/9116469/3795b21244c3/cureus-0014-00000024240-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fdf0/9116469/3795b21244c3/cureus-0014-00000024240-i01.jpg

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Efficacy and safety of Bacillus coagulans LBSC in irritable bowel syndrome: A prospective, interventional, randomized, double-blind, placebo-controlled clinical study [CONSORT Compliant].
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Int J Food Sci. 2025 Apr 14;2025:5567567. doi: 10.1155/ijfo/5567567. eCollection 2025.
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