Halemani Kurvatteppa, Issac Alwin, Mishra Prabhakar, Mathias Edlin
College of Nursing, Sanjay Gandhi Post Graduate Institute of Medical Sciences (SGPGIMS), Lucknow, Uttar Pradesh, India.
College of Nursing, All India Institute of Medical Sciences (AIIMS), Bhubaneswar, Odisha, India.
J Caring Sci. 2021 Nov 14;11(1):46-55. doi: 10.34172/jcs.2022.02. eCollection 2022 Mar.
Cancer is a leading cause of death among all age groups. Globally, cancer patients undergo one or more treatment modules, which often bring about fatigue, depression, anxiety, and muscle weakness. Therefore, this systemic review and meta-analysis aims to investigate randomized control trials (RCTs) on this subject. We conducted a systemic search of studies published in PubMed, MEDLINE, CINAHL, ClinicalKey, Cochrane Library, and Google scholar, in English language between 2005-2020. Two authors independently appraised the selected RCTs for evaluating the effectiveness of physical exercise on fatigue among patients undergoing adjuvant radiation therapy (RT). This systemic review and meta-analysis was conducted based on the Cochrane risk bias assessment tool, using RevMan 5.3 software. A total of 1440 participants from 12 trials were involved in the systemic review, 6 trials comprised 718 participants picked for meta-analysis. Physical exercise was found an effective intervention for reducing general fatigue and physical fatigue and some other variables (e.g. anxiety, depression, pain, quality of life, and sleep pattern) among patients undergoing adjuvant radiotherapy in the treatment group as compared to the control group. Physical exercise is an effective intervention on multidimensional fatigue among patients undergoing adjuvant RT. The studies are registered with PROSPERO and available in online.
癌症是所有年龄组中主要的死亡原因之一。在全球范围内，癌症患者要接受一个或多个治疗模块，这往往会导致疲劳、抑郁、焦虑和肌肉无力。因此，本系统评价和荟萃分析旨在调查关于该主题的随机对照试验（RCT）。我们对2005年至2020年间发表在PubMed、MEDLINE、CINAHL、ClinicalKey、Cochrane图书馆和谷歌学术上的英文研究进行了系统检索。两位作者独立评估所选的随机对照试验，以评估体育锻炼对接受辅助放疗（RT）患者疲劳的有效性。本系统评价和荟萃分析是基于Cochrane风险偏倚评估工具，使用RevMan 5.3软件进行的。共有来自12项试验的1440名参与者参与了系统评价，6项试验包括718名参与者被选入荟萃分析。与对照组相比，在治疗组中，体育锻炼被发现是一种有效的干预措施，可减轻接受辅助放疗患者的全身疲劳和身体疲劳以及其他一些变量（如焦虑、抑郁、疼痛、生活质量和睡眠模式）。体育锻炼是对接受辅助放疗患者多维疲劳的有效干预措施。这些研究已在PROSPERO注册并可在线获取。
