Dhiraaj Sanjay, Thimmappa Latha, Issac Alwin, Halemani Kurvatteppa, Mishra Prabhaker, Mavinatop Anusha
Department of Anesthesiology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India.
College of Nursing, All India Institute of Medical Sciences, Kalyani, West Bengal, India.
J Caring Sci. 2022 Dec 3;12(1):14-24. doi: 10.34172/jcs.2023.31750. eCollection 2023 Feb.
The congenital cardiac diseases (CHDs) are the leading cause of death in children. The CHDs detection and management have greatly improved over the past few decades. This review aimed to assess the effectiveness of early enteral nutrition (EEN) on postoperative outcomes in infants undergoing congenital cardiac surgery. Electronic databases PubMed, Clinical Key, UpToDate, the Cochrane Library, and Google Scholar were searched for studies published in the English language, between 2004 and 2021. This review carried out based on PRISMA statement and studies qualities assessed using "Downs and Black score". Hospital stay, intensive care unit (ICU) stay, mechanical ventilation support, aortic cross clamping and cardiopulmonary bypass were as primary outcomes. Similarly infections, vomiting and mortality were as secondary outcomes of included studies. This review consists of 887 infants from 10 studies. Of these, 470 infants were assigned to the intervention group and 417 to the control group. The post-operative hospital stay shorted in the EEN group than the control group (SMD=-0.63, 95% CI: -1.03 to -0.22, I=87%). Similarly, EEN group lessen the ICU stay (SMD=-0.15, 95% CI: -0.42, 0.11, =0.0, I=71%), mechanical ventilation support (SMD=-0.31, 95% CI: -0.51, -08, =0.08, I=47%), aortic cross clamping (SMD=-0.92, 95% CI: -0.31, 2.4, =0.00, I=96%), and cardiopulmonary bypass (SMD=-0.0, 95% CI: -0.42 to 43, =0.00, I=71%). Secondary postoperative complications such as infections (RR=0.68, 95% CI: 0.43 to 1.08, =0.40, I=3%). vomiting (RR=1.47, 95% CI: 0.80 to 2.69, =0.90, I=0%) and postoperative mortality (RR=0.42, 95% CI: 0.03 to 5.82, =0.00: I=80%) significantly reduced. Postoperative outcomes were improved in the intervention group compared to the control group, including shorter hospital stays, ICU stays, mechanical ventilation, and less postoperative complications.
先天性心脏病（CHD）是儿童死亡的主要原因。在过去几十年里，先天性心脏病的检测和管理有了很大改善。本综述旨在评估早期肠内营养（EEN）对接受先天性心脏手术婴儿术后结局的有效性。检索了电子数据库PubMed、Clinical Key、UpToDate、考克兰图书馆和谷歌学术，以查找2004年至2021年间发表的英文研究。本综述依据PRISMA声明进行，并使用“唐斯和布莱克评分”评估研究质量。住院时间、重症监护病房（ICU）停留时间、机械通气支持、主动脉交叉钳夹和体外循环作为主要结局。同样，感染、呕吐和死亡率作为纳入研究的次要结局。本综述纳入了10项研究中的887名婴儿。其中，470名婴儿被分配到干预组，417名婴儿被分配到对照组。EEN组术后住院时间比对照组缩短（标准化均数差=-0.63，95%可信区间：-1.03至-0.22，I²=87%）。同样，EEN组缩短了ICU停留时间（标准化均数差=-0.15，95%可信区间：-0.42，0.11，I²=0.0，I²=71%）、机械通气支持时间（标准化均数差=-0.31，95%可信区间：-0.51，-0.08，I²=0.08，I²=47%）、主动脉交叉钳夹时间（标准化均数差=-0.92，95%可信区间：-0.31，-2.4，I²=0.00，I²=96%）和体外循环时间（标准化均数差=-0.（此处原文有误，应为0.00），95%可信区间：-0.42至0.43，I²=0.00，I²=71%）。术后感染（风险比=0.68，95%可信区间：0.43至1.08，I²=0.40，I²=3%）、呕吐（风险比=1.47，95%可信区间：0.8
