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改良版 COVID-19 约克郡康复量表(C19-YRSm)用于长新冠或新冠后综合征的患者报告结局测量工具。

The modified COVID-19 Yorkshire Rehabilitation Scale (C19-YRSm) patient-reported outcome measure for Long Covid or Post-COVID-19 syndrome.

机构信息

Academic Department of Rehabilitation Medicine, University of Leeds, Leeds, UK.

National Demonstration Centre of Rehabilitation Medicine, Leeds Teaching Hospitals NHS Trust, Leeds, UK.

出版信息

J Med Virol. 2022 Sep;94(9):4253-4264. doi: 10.1002/jmv.27878. Epub 2022 Jun 1.

Abstract

BACKGROUND

The C19-YRS is the literature's first condition-specific, validated scale for patient assessment and monitoring in Post-COVID-19 syndrome (PCS). The 22-item scale's subscales (scores) are symptom severity (0-100), functional disability (0-50), additional symptoms (0-60), and overall health (0-10).

OBJECTIVES

This study aimed to test the scale's psychometric properties using Rasch analysis and modify the scale based on analysis findings, emerging information on essential PCS symptoms, and feedback from a working group of patients and professionals.

METHODS

Data from 370 PCS patients were assessed using a Rasch Measurement Theory framework to test model fit, local dependency, response category functioning, differential item functioning, targeting, reliability, and unidimensionality. The working group undertook iterative changes to the scale based on the psychometric results and including essential symptoms.

RESULTS

Symptom severity and functional disability subscales showed good targeting and reliability. Post hoc rescoring suggested that a 4-point response category structure would be more appropriate than an 11-point response for both subscales. Symptoms with binary responses were placed in the other symptoms subscale. The overall health single-item subscale remained unchanged.

CONCLUSION

A 17-item C19-YRSm was developed with subscales (scores): symptom severity (0-30), functional disability (0-15), other symptoms (0-25), and overall health (0-10).

摘要

背景

C19-YRS 是文献中第一个针对 COVID-19 后综合征(PCS)患者评估和监测的特定于疾病的、经过验证的量表。该 22 项量表的分量表(分数)为症状严重程度(0-100)、功能障碍(0-50)、附加症状(0-60)和总体健康(0-10)。

目的

本研究旨在使用 Rasch 分析测试该量表的心理测量特性,并根据分析结果、PCS 基本症状的新信息以及患者和专业人员工作组的反馈,对量表进行修改。

方法

使用 Rasch 测量理论框架评估 370 名 PCS 患者的数据,以测试模型拟合、局部依赖性、反应类别功能、差异项目功能、目标、可靠性和单维性。工作组根据心理测量结果和包括基本症状在内的信息,对量表进行迭代修改。

结果

症状严重程度和功能障碍分量表显示出良好的目标和可靠性。事后重新评分表明,对于两个分量表,4 点反应类别结构比 11 点反应类别结构更合适。具有二进制响应的症状被放置在其他症状分量表中。整体健康单项目分量表保持不变。

结论

开发了一个包含分量表(分数)的 17 项 C19-YRSm:症状严重程度(0-30)、功能障碍(0-15)、其他症状(0-25)和总体健康(0-10)。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/83e1/9348420/7e500e669e0d/JMV-94-4253-g003.jpg

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