2013-2020 年期间就诊于阿德亚曼培训与研究医院的疑似包虫病患者的血清学结果回顾性评估。
A Retrospective Evaluation of Serological Results of Cystic Echinococcosis Suspected Cases Admitted to Adıyaman Training and Research Hospital Between 2013-2020.
机构信息
Adıyaman Üniversitesi Tıp Fakültesi, Mikrobiyoloji Anabilim Dalı, Adıyaman, Türkiye
İnönü Üniversitesi Tıp Fakültesi, Biyoistatistik ve Tıp Bilişimi Anabilim Dalı, Malatya, Türkiye
出版信息
Turkiye Parazitol Derg. 2022 May 23;46(2):140-144. doi: 10.4274/tpd.galenos.2021.29591.
OBJECTIVE
Cystic echinococcosis (CE) is prevalent, especially in animals in Turkey and stands as a significant zoonose. In this study, we aimed to retrospectively evaluate the indirect hemagglutination (IHA) tests results performed on samples of CE suspected patients in microbiology laboratory of our hospital.
METHODS
One thousand six hundred-seven files of patients admitted to hospital between January 2013 and December 2020 were examined for the presence of anti- immunoglobulin G antibodies. The patient's socio-demographic characteristics and radiological data were obtained from the hospital automatization system.
RESULTS
A total of 1.607 file records; 644 (40.1%) males and 963 (59.9%) females, aged between 1-96 years (average 45.26±19.91) were examined. It was found that 244 (15.18%) of the patients were positive, 78 (4.86%) were determined at an intermediary value and 1.285 (79.96%) were negative. According to the IHA method a titer of 1/320 and above were evaluated as positive. Compared to anti- IgG antibody titers 164 radiological data; while 28.6% of 21 patients who are evaluated as negative (1/80) and 46.2% of 78 patients who were evaluated as intermediary titer (1/160) had cystic lesion in the radiological findings.
CONCLUSION
Based on the data, it is suggested that while interpreting the patient's serum antibody titers, patient's clinical and radiological findings should also be taken into account. If possible, it should be used along with another serological method like ELISA to assist CE patient's diagnosis and treatment.
目的
包虫病（CE）在土耳其尤为流行，是一种重要的人畜共患病。本研究旨在回顾性评估我院微生物实验室对疑似 CE 患者样本进行间接血凝（IHA）检测的结果。
方法
对 2013 年 1 月至 2020 年 12 月期间入院的 1670 例患者的文件进行检查，以检测抗免疫球蛋白 G 抗体。从医院自动化系统中获取患者的社会人口统计学特征和影像学数据。
结果
共检查了 1607 份文件记录，其中男性 644 例（40.1%），女性 963 例（59.9%），年龄在 1-96 岁之间（平均年龄 45.26±19.91）。发现 244 例（15.18%）患者为阳性，78 例（4.86%）为中间值，1285 例（79.96%）为阴性。根据 IHA 方法，将滴度≥1/320 判定为阳性。与抗 IgG 抗体滴度相比，164 份影像学数据中，28.6%的 21 例阴性（1/80）患者和 46.2%的 78 例中间值（1/160）患者的影像学检查存在囊性病变。
结论
根据这些数据，建议在解释患者血清抗体滴度时，还应考虑患者的临床和影像学表现。如有可能，应与 ELISA 等其他血清学方法一起使用，以协助 CE 患者的诊断和治疗。
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