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[通过显微荧光测定法确定的小甲状腺乳头状癌中的核DNA含量]

[Nuclear DNA content in small thyroid papillary carcinomas determined by microfluorometry].

作者信息

Omata K, Naoe S, Tanaka N

出版信息

Gan No Rinsho. 1987 Feb;33(2):119-24.

PMID:3560446
Abstract

Microfluorometric measurement of the DNA content of cell nuclei was performed on echo-guided aspiration specimens or imprints of operated fresh materials of fourty-one small thyroid papillary carcinomas of 10 mm or less in diameter and of six large ones more than 20 mm in diameter. The distribution patterns of the DNA content were classified into three groups: IIa, IIb and III. The DNA values in so-called sclerosing carcinomas mostly fell into Group-IIa, while ordinary papillary carcinomas were classified as Group-IIb and III. Our date suggests that the DNA microfluorometry of echo-guided aspiration specimens of small papillary carcinomas gives the index whether they will remain occult or not.

摘要

对41例直径10毫米及以下的小甲状腺乳头状癌和6例直径超过20毫米的大甲状腺乳头状癌的手术新鲜材料的回声引导穿刺标本或印片进行了细胞核DNA含量的显微荧光测定。DNA含量的分布模式分为三组:IIa、IIb和III。所谓硬化性癌的DNA值大多属于IIa组,而普通乳头状癌则分为IIb组和III组。我们的数据表明,对小乳头状癌的回声引导穿刺标本进行DNA显微荧光测定可得出它们是否会隐匿的指标。

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