Vascular Medicine Unit, Cardio-Vascular Center, University Hospital of Poitiers, Poitiers, France.
Department of Internal Medicine, University Hospital of Poitiers, Poitiers, France.
J Cardiovasc Transl Res. 2023 Feb;16(1):141-151. doi: 10.1007/s12265-022-10276-3. Epub 2022 May 23.
Right atrial pressure (RAP) is an important prognostic criterion in pulmonary hypertension (PH). The main goals were to evaluate the following: (i) the accuracy of Doppler assessment of common femoral vein flow waveform to detect elevated RAP and (ii) the diagnostic accuracy of RAP assessed by echocardiography (eRAP). Fifty-seven patients, addressed for right heart catheterization, were included in a retrospective cross-sectional study during a 6-month period. Forty-five patients (78.9%) had PH confirmed by RHC. Elevated RAP was defined by RAP ≥ 10 mmHg. Femoral venous stasis index (FVSI) was highly correlated to RAP on both univariate (p < 0.001) and multivariate analysis (p = 0.003), and showed good diagnostic performances to detect elevated RAP (specificity: 92.3% [80.0-99.3], diagnosis accuracy: 90.4 [77.4-97.3], positive likelihood ratio: 12.5 [3.01-51.97]). Diagnosis accuracy of eRAP was only 51.2% (36.2-66.1). FVSI is independently correlated to RAP and a useful tool to predict elevated RAP in PH patients.
右心房压(RAP)是肺动脉高压(PH)的一个重要预后标准。主要目的是评估以下内容:(i)多普勒评估股总静脉血流波形以检测升高的 RAP 的准确性,以及(ii)超声心动图(eRAP)评估 RAP 的诊断准确性。在 6 个月的时间内,对因右心导管检查而就诊的 57 例患者进行了回顾性横断面研究。45 例患者(78.9%)通过 RHC 证实存在 PH。RAP 升高定义为 RAP≥10mmHg。股静脉淤滞指数(FVSI)在单变量(p<0.001)和多变量分析(p=0.003)中均与 RAP 高度相关,并且具有良好的诊断性能来检测升高的 RAP(特异性:92.3%[80.0-99.3],诊断准确性:90.4%[77.4-97.3],阳性似然比:12.5[3.01-51.97])。eRAP 的诊断准确性仅为 51.2%(36.2-66.1)。FVSI 与 RAP 独立相关,是预测 PH 患者升高 RAP 的有用工具。