Sanders Allix M, Dawidczyk Thomas J, Katz Howard E, Tovar John D
Department of Chemistry, ‡Department of Materials Science and Engineering, §Institute for NanoBioTechnology, Johns Hopkins University, 3400 North Charles Street, Baltimore, Maryland 21218, United States.
Department of Chemistry, Department of Materials Science and Engineering, §Institute for NanoBioTechnology, Johns Hopkins University, 3400 North Charles Street, Baltimore, Maryland 21218, United States.
ACS Macro Lett. 2012 Nov 20;1(11):1326-1329. doi: 10.1021/mz3004665. Epub 2012 Oct 30.
We report a streamlined method for the synthesis of peptides embedded with complex and easily variable π-conjugated oligomeric subunits from commercially available precursors. These modified peptides self-assemble under aqueous conditions to form one-dimensional nanomaterials containing networks of π-stacked conduits, despite the inclusion of π-conjugated oligomers with quadrupoles extended over larger areas. The procedure has circumvented solubility and other synthetic issues to allow for the facile formation of a diverse library of bioelectronic nanomaterials, including a complex sexithiophene-containing peptide whose nanostructures display gate-induced conductivity within field effect transistors.
我们报道了一种简化的方法，用于从市售前体合成嵌入复杂且易于变化的π共轭低聚亚基的肽。这些修饰的肽在水性条件下自组装形成一维纳米材料，其中包含π堆积导管网络，尽管包含具有在更大区域扩展的四极子的π共轭低聚物。该方法规避了溶解性和其他合成问题，从而能够轻松形成各种生物电子纳米材料库，包括一种含复杂六噻吩的肽，其纳米结构在场效应晶体管中显示出门控诱导的导电性。
