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广泛的黄斑萎缩伴假性类 drusen:病例系列和综述。

Extensive macular atrophy with pseudodrusen-like: Case series and review.

机构信息

Federal University of Health Sciences of Porto Alegre, Brazil.

University Vita-Salute, Milan, Italy.

出版信息

Eur J Ophthalmol. 2023 Jul;33(4):NP80-NP84. doi: 10.1177/11206721221102269. Epub 2022 May 23.

DOI:10.1177/11206721221102269
PMID:35607265
Abstract

PURPOSE

To describe the clinical characteristics of two patients affected by extensive macular atrophy with pseudodrusen-like (EMAP).

METHODS

Two patients affected by EMAP underwent multimodal imaging, including fundus autofluorescence and optical coherence tomography.

RESULTS

The patients showed the typical clinical appearance with macular atrophy with larger vertical axis surrounded by pseudodrusen-like deposits involving the midperiphery, associated with paving stone lesions in the retinal periphery.

CONCLUSION

EMAP is a complex condition sharing clinical characteristics of age-related macular degeneration. Further studies are warranted to identify the early biomarker of the disease.

摘要

目的

描述 2 例广泛型黄斑萎缩伴假性类 drusen(EMAP)患者的临床特征。

方法

对 2 例 EMAP 患者进行多模态成像,包括眼底自发荧光和光学相干断层扫描。

结果

患者表现出典型的临床特征,即黄斑萎缩伴垂直轴较大,周围有假性类 drusen 样沉积物,累及中周边部,伴视网膜周边铺路石样病变。

结论

EMAP 是一种具有年龄相关性黄斑变性临床特征的复杂疾病。需要进一步研究以确定疾病的早期生物标志物。

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Extensive macular atrophy with pseudodrusen-like appearance: comprehensive review of the literature.广泛的黄斑萎缩伴假性德鲁森样外观:文献综述。
Graefes Arch Clin Exp Ophthalmol. 2024 Oct;262(10):3085-3097. doi: 10.1007/s00417-024-06600-z. Epub 2024 Aug 12.
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Intelligent Diagnosis of Multiple Peripheral Retinal Lesions in Ultra-widefield Fundus Images Based on Deep Learning.基于深度学习的超广角眼底图像中多种周边视网膜病变的智能诊断
Ophthalmol Ther. 2023 Apr;12(2):1081-1095. doi: 10.1007/s40123-023-00651-x. Epub 2023 Jan 24.